Post-translational modification of Tau, a microtubule-associated protein in the neuronal cell,
plays a major role in Alzheimer's disease. Tau is an axonal protein expressed in mature …

Glucose homeostasis is the maintenance and regulation of blood glucose concentration
within a tight physiological range, essential for the functioning of most tissues and organs …

The aim of this study was to explore individual amino acid-stimulated GLP-1 responses and
the underlying stimulatory mechanisms, as well as to identify the amino acid-sensing …

Chronic diseases, especially cardiovascular diseases (CVD), have become one of the main
causes affecting human health. Hypertension is a prominent representative of CVD. The …

Pre-mRNA processing factor 4B (PRP4) has previously been shown to induce epithelial-
mesenchymal transition (EMT) and drug resistance in cancer cell lines. As melanin plays an …

Over the recent decades, a number of new pathogens have emerged within specific and
diverse populations across the globe, namely, the Nipah virus, the Ebola virus, the Zika …

Sepsis is a life‐threatening disease involving multiorgan dysfunction, prompted by an
unregulated host response to infection. Shock is a complication of sepsis in which the …

A quarter of a century ago, designer peptide drugs finally broke through the glass ceiling.
Despite the resistance by big pharma, biotechnology companies managed to develop …

Bioactive glass has been employed in several medical applications since its inception in
1969. The compositions of these materials have been investigated extensively with …

Abstract Calcium (Ca 2+) homeostasis is crucial for maintaining physiological processes in
the body, and disruptions in Ca 2+ signaling can lead to various pathological conditions …