Obesity usually is accompanied by inflammation of fat tissue, with a prominent role of
visceral fat. Chronic inflammation in obese fat tissue is of a lower grade than acute immune …

Compelling experimental evidence links immunity and metabolism. In this perspective, we
propose forkhead-box-P3 (FoxP3)+ CD4+ CD25+ regulatory T (Treg) cells as key metabolic …

Unhealthy dietary patterns-induced obesity and obesity-related complications pose a great
threat to human health all over the world. Accumulating evidence suggests that the …

The immune response is tailored to the environment in which it takes place. Immune cells
sense and adapt to changes in their surroundings, and it is now appreciated that in addition …

Obesity, diabetes mellitus (mostly type 2), and COVID-19 show mutual interactions because
they are not only risk factors for both acute and chronic COVID-19 manifestations, but also …

The study of adipose tissue (AT) is enjoying a renaissance. White, brown, and beige
adipocytes are being investigated in adult animals, and the critical roles of small depots like …

Metabolism is a core process underlying essentially all biological functions. The integration
of metabolism with immunity, known as immunometabolism, is at the forefront of immunology …

The mechanisms underlying glucocorticoid (GC)-induced obesity are poorly understood.
Macrophages are the primary targets by which GCs exert pharmacological effects and …

Recent studies have demonstrated that tissue homeostasis and metabolic function are
dependent on distinct tissue-resident immune cells that form functional cell circuits with …

The expansion of adipose tissue is an adaptive mechanism that increases nutrient buffering
capacity in response to an overall positive energy balance. Over the course of expansion …