[HTML][HTML] Genome-wide sex and gender differences in cancer
CM Lopes-Ramos, J Quackenbush… - Frontiers in oncology, 2020 - frontiersin.org
Despite their known importance in clinical medicine, differences based on sex and gender
are among the least studied factors affecting cancer susceptibility, progression, survival, and …
are among the least studied factors affecting cancer susceptibility, progression, survival, and …
Post-diagnosis smoking cessation and survival of patients with head and neck cancer: a systematic review and meta-analysis
Cigarette smoking is the main risk factor for head and neck cancer (HNC) and many HNC
patients are active smokers at diagnosis. We conducted a systematic literature review and …
patients are active smokers at diagnosis. We conducted a systematic literature review and …
[HTML][HTML] Gender disparities in epidemiology, treatment, and outcome for head and neck cancer in Germany: a population-based long-term analysis from 1996 to 2016 …
A Dittberner, B Friedl, A Wittig, J Buentzel, H Kaftan… - Cancers, 2020 - mdpi.com
Simple Summary Head and neck cancer (HNC) comprises a heterogeneous group of
cancers. Not much population-based data has been published on gender disparities related …
cancers. Not much population-based data has been published on gender disparities related …
[HTML][HTML] Are sex and gender considered in head and neck cancer clinical studies?
We analyzed the inclusion of sex and/or gender (S/G) in Head and Neck Cancer (HNC)
clinical studies, through inspecting ClinicalTrials. gov (AACT) and the mention of Human …
clinical studies, through inspecting ClinicalTrials. gov (AACT) and the mention of Human …
All HPV-negative head and neck cancers are not the same: Analysis of the TCGA dataset reveals that anatomical sites have distinct mutation, transcriptome, hypoxia …
Purpose Head and neck squamous cell carcinoma (HNSCC) affects various anatomical
sites, which often dictates whether the cancer is managed with primary surgery or radiation …
sites, which often dictates whether the cancer is managed with primary surgery or radiation …
BRWD3 promotes KDM5 degradation to maintain H3K4 methylation levels
D Han, SH Schaffner, JP Davies… - Proceedings of the …, 2023 - National Acad Sciences
Histone modifications are critical for regulating chromatin structure and gene expression.
Dysregulation of histone modifications likely contributes to disease states and cancer …
Dysregulation of histone modifications likely contributes to disease states and cancer …
Sex, immunity, and cancer
The composition of the tumor microenvironment is the complex result of the interaction
between tumoral and host factors. Since there are several differences in the regulation of …
between tumoral and host factors. Since there are several differences in the regulation of …
[HTML][HTML] Sex-specific gene expression patterns in head and neck squamous cell carcinomas
S Wang, W Pan, W Mi, S Wang - Heliyon, 2023 - cell.com
Objective The head and neck squamous cell carcinomas (HNSCCs) have higher incidence
rates in men, but the reasons are still obscure. This study aimed to investigate the sex …
rates in men, but the reasons are still obscure. This study aimed to investigate the sex …
Genomic characterization of lymphomas in patients with inborn errors of immunity
X Ye, PJ Maglione, C Wehr, X Li, Y Wang… - Blood …, 2022 - ashpublications.org
Patients with inborn errors of immunity (IEI) have a higher risk of developing cancer,
especially lymphoma. However, the molecular basis for IEI-related lymphoma is complex …
especially lymphoma. However, the molecular basis for IEI-related lymphoma is complex …
A combination of intra-tumor genetic heterogeneity, estrogen receptor alpha and human papillomavirus status predicts outcomes in head and neck squamous cell …
Background Previous work indicates that mutant-allele tumor heterogeneity (MATH),
estrogen receptor alpha (ERα) expression, and human papillomavirus (HPV) status provide …
estrogen receptor alpha (ERα) expression, and human papillomavirus (HPV) status provide …