Major differences between men and women exist in epidemiology, manifestation,
pathophysiology, treatment, and outcome of cardiovascular diseases (CVD), such as …

An increasing number of elderly men are receiving exogenous testosterone to treat
hypogonadism, low libido, and general weakness. 1 The impact of testosterone on the …

In the present study we have used hypopituitary Ames dwarf mice, which lack GH, prolactin
and TSH, to investigate the consequences of the deficiency of these hormones on glucose …

Important sex differences in the onset and characteristics of cardiovascular disease are
evident, yet the mechanistic details remain unresolved. Men are more susceptible to …

Alzheimer's disease (AD) is the most common form of dementia, with over 5. 4 million cases
in the US alone (Alzheimer's Association, 2016). Clinically, AD is defined by the presence of …

Cardiovascular disease (CVD) prevalence, pathogenesis, and manifestation is differentially
influenced by biological sex. Berry polyphenols target several signaling pathways pertinent …

Background Although testosterone deficiency is associated with increased risks of heart
disease, the benefits of testosterone therapy are controversial. Moreover, current …

Objective—Calcific aortic valve disease is the most prevalent valvulopathy in Western
countries. An unanticipated pathogenetic clue involving IFN (interferon) was disclosed by …

Traumatic brain injury (TBI) is known as an acute degenerative pathology of the central
nervous system, and has been shown to increase brain aquaporin 4 (AQP4) expression …

The damage of vascular endothelial cells induced by oxidative stress plays an important role
in the pathogenesis of atherosclerosis. Dihydromyricetin (DMY) is considered as a natural …