Glycans are complex, yet ubiquitous across biological systems. They are involved in diverse
essential organismal functions. Aberrant glycosylation may lead to disease development …

Gastric cancer is a remarkably heterogeneous tumor. Despite some advances in the
diagnosis and treatment of gastric cancer in recent years, the precise treatment and curative …

Introduction Hepatocellular carcinoma (HCC) represents a significant burden globally, which
ranks sixth among the most frequently diagnosed cancers and stands as the third leading …

The heterogeneity inherent in today's biotherapeutics, especially as a result of heavy
glycosylation, can affect a molecule's safety and efficacy. Characterizing this heterogeneity …

Approximately thirty percent of the proteins synthesized in animal or plant cells travel
through the secretory pathway. Seventy to eighty percent of those proteins are glycosylated …

N-glycosylation is a complex mechanism in which the carbohydrate molecules bind to the
Asn amino acid in the N-glycan consensus sequence (AsnXxxThr/Ser sequon, where Xxx is …

Glycosylation is the most common post-translational modification of protein in all territories,
which plays a significant role in biological processes. Amongst them, n-linked glycosylation …