A mammalian monothiol glutaredoxin, Grx3, is critical for cell cycle progression during embryogenesis

NH Cheng, W Zhang, WQ Chen, J Jin, X Cui… - The FEBS …, 2011 - Wiley Online Library
Glutaredoxins (Grxs) have been shown to be critical in maintaining redox homeostasis in
living cells. Recently, an emerging subgroup of Grxs with one cysteine residue in the …

A Disruption in Iron-Sulfur Center Biogenesis via Inhibition of Mitochondrial Dithiol Glutaredoxin 2 May Contribute to Mitochondrial and Cellular Iron Dysregulation in …

DW Lee, D Kaur, SJ Chinta, S Rajagopalan… - Antioxidants & redox …, 2009 - liebertpub.com
Parkinson's disease (PD) is characterized by early glutathione depletion in the substantia
nigra (SN). Among its various functions in the cell, glutathione acts as a substrate for the …

Grain subproteome responses to nitrogen and sulfur supply in diploid wheat Triticum monococcum ssp. monococcum

T Bonnot, E Bancel, D Alvarez, M Davanture… - The Plant …, 2017 - Wiley Online Library
Wheat grain storage proteins (GSP s) make up most of the protein content of grain and
determine flour end‐use value. The synthesis and accumulation of GSP s depend highly on …

Identification of potential inhibitors of Fasciola gigantica thioredoxin1: computational screening, molecular dynamics simulation, and binding free energy studies

R Shukla, H Shukla, P Kalita, A Sonkar… - Journal of …, 2018 - Taylor & Francis
Fasciola gigantica is the causative organism of fascioliasis and is responsible for major
economic losses in livestock production globally. F. gigantica thioredoxin1 (FgTrx1) is an …

A Novel Group of Glutaredoxins in the cis-Golgi Critical for Oxidative Stress Resistance

N Mesecke, A Spang, M Deponte… - Molecular biology of the …, 2008 - Am Soc Cell Biol
Glutaredoxins represent a ubiquitous family of proteins that catalyze the reduction of
disulfide bonds in their substrate proteins by use of reduced glutathione. In an attempt to …

[HTML][HTML] Frenolicin B targets peroxiredoxin 1 and glutaredoxin 3 to trigger ROS/4E-BP1-mediated antitumor effects

Q Ye, Y Zhang, Y Cao, X Wang, Y Guo, J Chen… - Cell chemical …, 2019 - cell.com
Summary Peroxiredoxin 1 (Prx1) and glutaredoxin 3 (Grx3) are two major antioxidant
proteins that play a critical role in maintaining redox homeostasis for tumor progression …

Mentha piperita essential oil induces apoptosis in yeast associated with both cytosolic and mitochondrial ROS-mediated damage

P Ferreira, T Cardoso, F Ferreira… - FEMS yeast …, 2014 - academic.oup.com
Mentha piperita (MP), also known as peppermint, is an aromatic and medicinal plant widely
used in the food industry, perfumery and cosmetic, pharmacy and traditional medicine. Its …

Glutathione-dependent redox status of frataxin-deficient cells in a yeast model of Friedreich's ataxia

F Auchère, R Santos, S Planamente… - Human molecular …, 2008 - academic.oup.com
Friedreich′ s ataxia is a neurodegenerative disease caused by reduced expression of the
mitochondrial protein frataxin. The main phenotypic features of frataxin-deficient human and …

[HTML][HTML] Molecular chaperones involved in mitochondrial iron–sulfur protein biogenesis

R Dutkiewicz, M Nowak - JBIC Journal of Biological Inorganic Chemistry, 2018 - Springer
Iron–sulfur (FeS) clusters are prosthetic groups critical for the function of many proteins in all
domains of life. FeS proteins function in processes ranging from oxidative phosphorylation …

Glutaredoxins in plant development, abiotic stress response, and iron homeostasis: From model organisms to crops

Q Wu, J Yang, N Cheng, KD Hirschi, FF White… - … and Experimental Botany, 2017 - Elsevier
Plant growth, development, and response to environmental stress require the judicious
balance of reactive oxygen species (ROS). Glutaredoxins (GRXs) are a group of …