Depression in heart failure: a meta-analytic review of prevalence, intervention effects, and associations with clinical outcomes

T Rutledge, VA Reis, SE Linke, BH Greenberg… - Journal of the American …, 2006 - jacc.org
This article describes a meta-analysis of published associations between depression and
heart failure (HF) in regard to 3 questions: 1) What is the prevalence of depression among …

Mechanisms of cardiovascular toxicities associated with immunotherapies

AH Baik, OO Oluwole, DB Johnson, N Shah… - Circulation …, 2021 - Am Heart Assoc
Immune-based therapies have revolutionized cancer treatments. Cardiovascular sequelae
from these treatments, however, have emerged as critical complications, representing new …

[HTML][HTML] Cardiac remodeling: endothelial cells have more to say than just NO

VFM Segers, DL Brutsaert… - Frontiers in physiology, 2018 - frontiersin.org
The heart is a highly structured organ consisting of different cell types, including myocytes,
endothelial cells, fibroblasts, stem cells, and inflammatory cells. This pluricellularity provides …

B-type natriuretic peptide exerts broad functional opposition to transforming growth factor-β in primary human cardiac fibroblasts: fibrosis, myofibroblast conversion …

AM Kapoun, F Liang, G O'Young, DL Damm… - Circulation …, 2004 - Am Heart Assoc
The natriuretic peptides, including human B-type natriuretic peptide (BNP), have been
implicated in the regulation of cardiac remodeling. Because transforming growth factor-β …

New targets to treat the structural remodeling of the myocardium

A González, S Ravassa, J Beaumont, B López… - Journal of the American …, 2011 - jacc.org
Classical therapy of heart failure is based on treatment of its pre-disposing/triggering factors
and of the neurohumoral activation secondary to the deterioration of cardiac function. A new …

Depression, healthcare utilization, and death in heart failure: a community study

AR Moraska, AM Chamberlain, ND Shah… - Circulation: Heart …, 2013 - Am Heart Assoc
Background—The increasing prevalence of heart failure (HF) and high associated costs
have spurred investigation of factors leading to adverse outcomes in patients with HF …

Protective effects of vanillic acid on electrocardiogram, lipid peroxidation, antioxidants, proinflammatory markers and histopathology in isoproterenol induced …

PSM Prince, S Rajakumar, K Dhanasekar - European journal of …, 2011 - Elsevier
Myocardial infarction affects a large proportion in the world. This study aims to evaluate the
protective effects of vanillic acid in isoproterenol induced cardiotoxic rats. Male Wistar rats …

Role of biomarkers in cardiac structure phenotyping in heart failure with preserved ejection fraction: critical appraisal and practical use

E D'Elia, M Vaduganathan, M Gori… - European journal of …, 2015 - Wiley Online Library
Heart failure (HF) with preserved ejection fraction (HFpEF) is a heterogeneous clinical
syndrome characterized by cardiovascular, metabolic, and pro‐inflammatory diseases …

Targeting the vicious inflammation–oxidative stress cycle for the management of heart failure

N Khaper, S Bryan, S Dhingra, R Singal… - Antioxidants & redox …, 2010 - liebertpub.com
Oxidative stress and inflammation are each implicated independently in the development
and progression of heart failure. Their interaction, however, is also evident throughout the …

Soluble ST2 in heart failure with preserved ejection fraction

OF AbouEzzeddine, PM McKie, SM Dunlay… - Journal of the …, 2017 - Am Heart Assoc
Background Soluble ST2 is a biomarker that is elevated in certain systemic inflammatory
diseases. Comorbidity‐driven microvascular inflammation is postulated to play a key role in …