HIV-associated dementia (HAD) is an important complication of the central nervous system
in patients who are infected with HIV-1. Although the incidence of HAD has markedly …

Both calorie restriction and the ketogenic diet possess broad therapeutic potential in various
clinical settings and in various animal models of neurological disease. Following calorie …

The pathophysiology of sepsis and septic shock involves complex cytokine and
inflammatory mediator networks. NF-κB activation is a central event leading to the activation …

Apoptosis is likely to be the main form of beta-cell death in immune-mediated diabetes
mellitus in rodents and possibly in humans. Clarification of the regulation of beta-cell death …

The idea of the existence of an interaction between the immune system and the central
nervous system (CNS) has prompted extensive research interest into the subject of “ …

Accumulating evidence suggests that neurodegeneration induced by pathogenic proteins
depends on contributions from surrounding glia. Here we demonstrate that NF-κB signaling …

Aims: This is a review of preclinical studies covering alcohol-induced brain neuronal death
and loss of neurogenesis as well as abstinence-induced brain cell genesis, eg brain …

Exposure to complex mixtures of air pollutants produces infl ammation in the upper and
lower respiratory tract. Because the nasal cavity is a common portal of entry, respiratory and …

The receptor for advanced glycation end products (RAGE) is a transmembrane receptor of
the immunoglobulin superfamily, capable of binding a broad repertoire of ligands. RAGE …

Air pollution is a complex mixture of gases (eg, ozone), particulate matter, and organic
compounds present in outdoor and indoor air. Dogs exposed to severe air pollution exhibit …