Synthesis and initial evaluation of radioiodine-labelled deuterated tropane derivatives targeting dopamine transporter

J Liu, J Kang, M Qi, J Tang, Y Fang, C Liu… - Bioorganic & Medicinal …, 2024 - Elsevier
The dopamine transporter (DAT) is closely related to a variety of neurological disorders
including Parkinson's disease (PD) and other neurodegenerative diseases. In vivo imaging …

[18F]fluoride Activation and 18F-Labelling in Hydrous Conditions—Towards a Microfluidic Synthesis of PET Radiopharmaceuticals

O Ovdiichuk, S Lahdenpohja, Q Béen, L Tanguy… - Molecules, 2023 - mdpi.com
18F-labelled radiopharmaceuticals are indispensable in positron emission tomography. The
critical step in the preparation of 18F-labelled tracers is the anhydrous F-18 nucleophilic …

多巴胺转运蛋白显像探针18F-FP-CIT 的AllinOne 模块自动化制备及大鼠基底节Micro PET/CT 显像

屈骞, 海汪溪, 胡生焰, 张敏, 陈肖玥, 周熠磊… - 诊断学理论与 …, 2022 - qk.sjtu.edu.cn
目的: 验证AllinOne 模块自动化制备多巴胺转运蛋白(dopamine transporters, DAT) 显像探针18
氟-氮-(3-氟丙基)-2β-甲酯基-3β-(4′-碘苯基) 去甲基托烷[18 FN-(3-fluoropropyl)-2β …

Automated synthesis of dopamine transporters imaging probe 18F-FP-CIT based on allin one for Micro PET/CT imaging of rat basal ganglia

QU Qian, HAI Wangxi, HU Shengyan, Z Min… - Journal of Diagnostics …, 2022 - qk.sjtu.edu.cn
Objective: To verify the efficiency and stability of the automated labeling and synthesis of
dopamine transporters (DAT) imaging probe, 18 FN-(3-fluoropropyl)-2β-carbomethoxy-3β …