Human peripheral blood mononuclear cells: A review of recent proteomic applications
M Alexovič, JR Lindner, P Bober, R Longuespée… - …, 2022 - Wiley Online Library
Human peripheral blood mononuclear cells (PBMCs) represent a sentinel blood sample
which reacts to different pathophysiological stimuli in the form of immunological responses …
which reacts to different pathophysiological stimuli in the form of immunological responses …
[HTML][HTML] Current vaccine strategies and novel approaches to combatting Francisella infection
Tularemia is caused by subspecies of Francisella tularensis and can manifest in a variety of
disease states, with the pneumonic presentation resulting in the greatest mortality. Despite …
disease states, with the pneumonic presentation resulting in the greatest mortality. Despite …
Transcriptomic and Metabolic Responses to a Live-Attenuated Francisella tularensis Vaccine
The immune response to live-attenuated Francisella tularensis vaccine and its host evasion
mechanisms are incompletely understood. Using RNA-Seq and LC–MS on samples …
mechanisms are incompletely understood. Using RNA-Seq and LC–MS on samples …
Alterations in the human plasma lipidome in response to tularemia vaccination
Tularemia is a highly infectious and contagious disease caused by the bacterium Francisella
tularensis. To better understand human response to a live-attenuated tularemia vaccine and …
tularensis. To better understand human response to a live-attenuated tularemia vaccine and …
Novel Transcriptional and Translational Biomarkers of Tularemia Vaccine Efficacy in a Mouse Inhalation Model: Proof of Concept
Francisella tularensis subspecies tularensis (Ftt) is extremely virulent for humans when
inhaled as a small particle aerosol (< 5 µm). Inhalation of≥ 20 viable bacteria is sufficient to …
inhaled as a small particle aerosol (< 5 µm). Inhalation of≥ 20 viable bacteria is sufficient to …
Proteomics Fundamentals and Applications in Microbiology
G Wagner, GA Maia, JR Barr, H Moura - Recent Advancements in the … - taylorfrancis.com
Proteomics, the investigation of protein expression in cells and tissues, relies on intricate
methodologies such as protein separation, mass spectrometry (MS), and bioinformatics on a …
methodologies such as protein separation, mass spectrometry (MS), and bioinformatics on a …