Cholesterol is a multifaceted metabolite that is known to modulate processes in cancer,
atherosclerosis, and autoimmunity. A common denominator between these diseases …

This review will focus on how bile acids are being used in clinical trials to treat neurological
diseases due to their central involvement with the gut-liver-brain axis and their physiological …

Oxysterols are oxidized derivatives of cholesterol produced by enzymatic activity or non-
enzymatic pathways (auto-oxidation). The oxidation processes lead to the synthesis of about …

The present review aims to provide a complete and comprehensive summary of current
literature relevant to oxysterols and related diseases. Oxidation of cholesterol leads to the …

Oxysterols are the products of cholesterol oxidation. They have a wide range of effects on
several cells, organs, and systems in the body. Oxysterols also have an influence on the …

As an essential lipid, cholesterol is of great value in keeping cell homeostasis, being the
precursor of bile acid and steroid hormones, and stabilizing membrane lipid rafts. As a kind …

Multiple sclerosis (MS) is a central nervous system disease with complex pathogenesis,
including two main processes: immune-mediated inflammatory demyelination and …

Abstract The role of 27-hydroxycholesterol (27-OHC) in autoimmune diseases has become
a subject of intense research in recent years. This oxysterol, derived from cholesterol, has …

This study aims at evaluating the effect of a phenol-rich extract obtained from the
concentration and purification of olive mill wastewaters (added at a ratio of 87.5 and 175 mg …

Inflammatory bowel disease (IBD), a general term encompassing Crohn's disease (CD) and
ulcerative colitis (UC), and other conditions, is a chronic and relapsing autoimmune disease …