BACKGROUND Endometriosis is defined as the colonization and growth of endometrial
tissue at anatomic sites outside the uterine cavity. Up to 15% of reproductive-aged women in …

Prostate cancer (PC) is the most commonly diagnosed nonskin malignancy and the second
most common cause of cancer death among men in the United States. Epigenetics is the …

Background Histone modifications and DNA methylation are two major factors in epigenetic
phenomenon. Unlike the histone deacetylase inhibitors, which are known to exert …

Results: The most important epigenetic changes include DNA methylation, histone
modification and microRNA regulation. Both DNA hypomethylation and hypermethylation …

ETHNOPHARMACOLOGICAL RELEVANCE: Rosa rugosa Thunb.(Rosaceae) has been
traditionally used for treatments of diabetes, chronic inflammatory diseases, pain, and …

Exposure to an environmental endocrine disruptor (eg, vinclozolin) during embryonic
gonadal sex determination appears to alter the male germ line epigenome and …

Expression of the imprinted genes insulin-like growth factor 2 (IGF2) and H19 depends on
the methylation pattern of their common imprinting control region (ICR) located on …

Epigenetic changes including DNA methylation, histone modifications, chromatin
remodeling and microRNAs play critical roles in tumorigenesis and tumor development …

Histone acetylation, which is regulated by histone acetyltransferases (HATs) and
deacetylases, is an epigenetic mechanism that influences eukaryotic transcription …

Results During the last decade, many different types of epigenetic alterations of DNA have
been found to be associated with malignant renal tumors. This has led to the research of the …