Diabetes is a chronic metabolic disease that is increasing in prevalence and causes many
complications. Diabetic cardiomyopathy (DCM) is a complication of diabetes that is …

Protein O-linked β-N-acetylglucosamine (O-GlcNAc) modification (O-GlcNAcylation) is a
unique monosaccharide modification discovered in the early 1980s. With the technological …

Hepatitis B virus (HBV) infection is a major risk factor for hepatocellular carcinoma (HCC),
but its pathogenic mechanism remains to be explored. The RNA N6-methyladenosine (m6A) …

O-GlcNAcylation is a posttranslational modification that adds O-linked β-N-
acetylglucosamine (O-GlcNAc) to serine or threonine residues of many proteins. This protein …

The hexosamine biosynthetic pathway (HBP) produces uridine diphosphate N-
acetylglucosamine (UDP-GlcNAc) to facilitate O-linked GlcNAc (O-GlcNAc) protein …

Protein posttranslational modifications (PTMs) refer to the breaking or generation of covalent
bonds on the backbones or amino acid side chains of proteins and expand the diversity of …

Post-translational modification with O-linked β-N-acetylglucosamine (O-GlcNAc), a process
referred to as O-GlcNAcylation, occurs on a vast variety of proteins. Mounting evidence in …

O-GlcNAcylation is a conserved post-translational modification that attaches N-acetyl
glucosamine (GlcNAc) to myriad cellular proteins. In response to nutritional and hormonal …

Ferroptosis is a form of regulated cell death that is initiated by excessive lipid peroxidation
that results in plasma membrane damage and the release of damage-associated molecular …

Ferroptosis is a form of regulated cell death characterized by iron-dependent accumulation
of lipid hydroperoxides to lethal levels. YAP has been reported to play a pivotal role in …