Background Cultured meat forms part of the emerging field of cellular agriculture. Still an
early stage field it seeks to deliver products traditionally made through livestock rearing in …

In patients with chronic kidney disease (CKD), loss of cellular proteins increases the risks of
morbidity and mortality. Persistence of muscle protein catabolism in CKD results in striking …

Skeletal muscles play important roles in critical body functions and their injury or disease
can lead to limitation of mobility and loss of independence. Current treatments result in …

Prenatal and postnatal myogenesis share many cellular and molecular aspects. Myogenic
regulatory factors are basic Helix-Loop-Helix transcription factors that indispensably …

The progressive loss of muscle strength during aging is a common degenerative event of
unclear pathogenesis. Although muscle functional decline precedes age-related changes in …

The most important requirements of biomedical substitutes used in muscle tissue
regeneration are appropriate topographical cues and bioactive components for the induction …

Therapeutic approaches for musculoskeletal tissue regeneration commonly employ growth
factors (GFs) to influence neighboring cells and promote migration, proliferation, or …

Skeletal muscle injuries typically result from traumatic incidents such as combat injuries
where soft-tissue extremity injuries are present in one of four cases. Further, about 4.5 …

The pharmacology and toxicology of a broad variety of therapies and chemicals have
significantly improved with the aid of the increasing in vitro models of complex human …

Millions of Americans suffer from skeletal muscle injuries annually that can result in
volumetric muscle loss (VML), where extensive musculoskeletal damage and tissue loss …