Helicobacter pylori is classified by IARC/WHO as a definite human gastric carcinogen,
despite “inadequate experimental evidence.” To obtain direct evidence concerning this …

Helicobacter pylori has been assigned as a class 1 carcinogen because of its relation to
gastric adenocarcinoma. Chronic H. pylori infection may lead to severe gastritis, glandular …

Although various animal models have been developed to clarify gastric carcinogenesis,
apparent mechanism of gastric cancer was not clarified in recent years. Since the …

The conservative nature of animal evolution makes animal models the ideal tool for learning
about human biology. The Handbook of Laboratory Animal Science, Second Edition: Animal …

Many epidemiological studies have shown a strong association between chronic
Helicobacter pylori infection and the subsequent development of gastric carcinoma in …

ABSTRACT C57BL/6 mice were orally immunized with five weekly doses of 2 mg, 200 μg, or
2 μg of Helicobacter pylori (Sydney strain) whole-cell sonicate combined with cholera toxin …

Helicobacter pylori is associated with gastric disorders in humans and some experimental
animals, and possesses the luxS/type 2 autoinducer (AI-2) system. The effects of a specific …

Objective To establish a rat model of chronic atrophic gastritis and explore the factors
inducing atrophy. Methods In accordance with repeated orthogonal design of L8 (27), 60 …

Helicobacter pylori is considered to have a close association with gastric cancer. Many
epidemiological studies have shown a strong association between chronic H. pylori infection …

Background. p53 gene mutations are believed to play a critical role in the development of
gastric carcinoma. We examined the relation between Helicobacter pylori infection and p53 …