Background The signs and symptoms of Zika virus infection are usually mild and self-limited.
However, the disease has been linked to neurological complications such as Guillain-Barré …

Zika virus was discovered in East Africa in 1947 by the Rockefeller Foundation during
investigations on the ecology of yellow fever. Although it was subsequently shown to have …

Abstract Background Prenatal exposure to Zika virus has potential teratogenic effects, with a
wide spectrum of clinical presentation referred to as congenital Zika syndrome. Data on …

Objectives To estimate the rates of maternal-fetal transmission of Zika virus, adverse
fetal/neonatal outcomes, and subsequent rates of asymptomatic/symptomatic congenital …

Viral infections during pregnancy are associated with adverse pregnancy outcomes,
including maternal and fetal mortality, pregnancy loss, premature labor, and congenital …

Zika virus (ZIKV) is a flavivirus with teratogenic effects on fetal brain, but the spectrum of
ZIKV-induced brain injury is unknown, particularly when ultrasound imaging is normal. In a …

Initial reports of congenital Zika virus (ZIKV) infection focused on microcephaly at birth with
severe brain anomalies; the phenotype has broadened to include microcephaly that …

Congenital Zika syndrome (CZS) causes early brain development impairment by affecting
neural progenitor cells (NPCs). Here, we analyze NPCs from three pairs of dizygotic twins …

What is already known about the topic? The Zika virus (ZIKV) emergence and its
consequences during pregnancy led to an increasing number of data about the maternal …

Zika virus (ZIKV) infection is associated with congenital defects and pregnancy loss. Here,
we found that 26% of nonhuman primates infected with Asian/American ZIKV in early …