Background Irritable bowel syndrome (IBS) is a common and potential disabling functional
gastrointestinal disorder. Studies have revealed a possible association between IBS and …

Death by suicide is one of the leading causes of mortality worldwide. Because individuals
with chronic pain are at least twice as likely to report suicidal behaviors or to complete …

Managing irritable bowel syndrome (IBS) has attracted international attention because
single-agent therapy rarely relieves bothersome symptoms for all patients. The Japanese …

Background Approximately 10% of the general population and around one third of adult
patients in clinical populations suffer from functional somatic symptoms. These take many …

Suicidality is exceedingly prevalent in pain patients. Although the pathophysiology of this
link remains unclear, it may be potentially related to the partial congruence of physical and …

Importance There are limited data on the extent to which suicide mortality is associated with
specific pain conditions. Objective To examine the associations between clinical diagnoses …

Irritable Bowel Syndrome (IBS) is a multisymptom condition defined by abdominal pain,
abdominal discomfort, and abnormalities in stool form and frequency. 1 IBS is a highly …

Objectives: Anxiety and depression occur frequently in patients with functional
gastrointestinal disorders (FGIDs), but their precise prevalence is unknown. We addressed …

Irritable bowel syndrome (IBS) is a prevalent and expensive condition that significantly
impairs health-related quality of life (HRQOL) and reduces work productivity. Based on strict …

The irritable bowel syndrome (IBS) is a chronic abdominal symptom complex that is
heterogeneous in terms of its clinical presentation and underlying pathophysiology and …