Galectin-3 (Gal-3) regulates basic cellular functions such as cell–cell and cell–matrix
interactions, growth, proliferation, differentiation, and inflammation. It is not surprising …

Galectin-3 is a β-galactoside-binding lectin which is important in numerous biological
activities in various organs, including cell proliferation, apoptotic regulation, inflammation …

Understanding of dedifferentiation, an indicator of poo prognosis for patients with thyroid
cancer, has been hampered by imprecise and incomplete characterization of its …

de Boer RA, van Veldhuisen DJ, Gansevoort RT, Muller Kobold AC, van Gilst WH, Hillege
HL, Bakker SJL, van der Harst P (University of Groningen). The fibrosis marker galectin‐3 …

Several cell surface molecules including signalling receptors are internalized by clathrin-
independent endocytosis. How this process is initiated, how cargo proteins are sorted and …

Context Accurate classification of follicular-patterned thyroid lesions is not always an easy
task on routine surgical hematoxylin-eosin–stained or cytologic fine-needle aspiration …

A major breakthrough in the field of medical oncology has been the discovery of galectins
and their role in cancer development, progression and metastasis. In this review article we …

The prevalence of thyroid carcinoma is increasing and represents the most common
endocrine malignancy, with papillary thyroid carcinoma (PTC) being the most frequent …

Simple Summary Galectins are a family of lectins that function to recognize carbohydrate
groups, such as those on glycosylated proteins. Throughout tumor development, changes in …

To interrogate the complex mechanisms involved in the later stages of cancer metastasis,
we designed a functional in vivo RNA interference (RNAi) screen combined with next …