Electrospun polymer micro/nanofibers as pharmaceutical repositories for healthcare

X Feng, J Li, X Zhang, T Liu, J Ding, X Chen - Journal of Controlled …, 2019 - Elsevier
Electrospun polymer micro/nanofibers have been widely explored as platforms for controlled
delivery of therapeutic agents. Electrospun fibers are featured by large surface area, high …

An overview of polymeric nanomicelles in clinical trials and on the market

X Zheng, J Xie, X Zhang, W Sun, H Zhao, Y Li… - Chinese Chemical …, 2021 - Elsevier
Polymeric nanomedicine is a promising and rapidly evolving field. Among the different
polymeric carriers, polymeric micelle (PM) with nanoscale size exhibit potent physical and …

An update on actively targeted liposomes in advanced drug delivery to glioma

S Mojarad-Jabali, M Farshbaf, PR Walker… - International Journal of …, 2021 - Elsevier
High-grade glioma is one of the most aggressive types of cancer with a low survival rate
ranging from 12 to 15 months after the first diagnosis. Though being the most common …

Self-assembled organic nanomaterials for drug delivery, bioimaging, and cancer therapy

Y Zhang, F Fang, L Li, J Zhang - ACS Biomaterials Science & …, 2020 - ACS Publications
Over the past few decades, tremendous progress has been made in the development of
engineering nanomaterials, which opened new horizons in the field of diagnosis and …

Immune escape in glioblastoma multiforme and the adaptation of immunotherapies for treatment

JRD Pearson, S Cuzzubbo, S McArthur… - Frontiers in …, 2020 - frontiersin.org
Glioblastoma multiforme (GBM) is the most frequently occurring primary brain tumor and has
a very poor prognosis, with only around 5% of patients surviving for a period of 5 years or …

Recent advances in drug delivery systems for targeting brain tumors

Y Zhao, P Yue, Y Peng, Y Sun, X Chen, Z Zhao… - Drug delivery, 2023 - Taylor & Francis
Brain tumor accounts for about 1.6% of incidence and 2.5% of mortality of all tumors, and the
median survival for brain tumor patients is only about 20 months. The treatment for brain …

Facilitating the translation of nanomedicines to a clinical product: challenges and opportunities

V Agrahari, V Agrahari - Drug Discovery Today, 2018 - Elsevier
Highlights•Clinical translation and commercialization challenges of nanomedicine products.•
Manufacturing or scale-up, characterization, safety, stability and efficacy …

Nasal drug delivery of anticancer drugs for the treatment of glioblastoma: preclinical and clinical trials

FA Bruinsmann, G Richter Vaz… - Molecules, 2019 - mdpi.com
Glioblastoma (GBM) is the most lethal form of brain tumor, being characterized by the rapid
growth and invasion of the surrounding tissue. The current standard treatment for …

Nanoformulation properties, characterization, and behavior in complex biological matrices: Challenges and opportunities for brain-targeted drug delivery applications …

V Agrahari, PA Burnouf, T Burnouf… - Advanced Drug Delivery …, 2019 - Elsevier
Nanocarriers (synthetic/cell-based have attracted enormous interest for various therapeutic
indications, including neurodegenerative disorders. A broader understanding of the impact …

A NIR-II-emitting gold nanocluster-based drug delivery system for smartphone-triggered photodynamic theranostics with rapid body clearance

Y Kong, D Santos-Carballal, D Martin, NN Sergeeva… - Materials Today, 2021 - Elsevier
Nanomedicine has grown structurally complex in order to perform multiple tasks at a time.
However, their unsatisfied reliability, uniformity and reproducibility account for the high rates …