Electrospun polymer micro/nanofibers as pharmaceutical repositories for healthcare
X Feng, J Li, X Zhang, T Liu, J Ding, X Chen - Journal of Controlled …, 2019 - Elsevier
Electrospun polymer micro/nanofibers have been widely explored as platforms for controlled
delivery of therapeutic agents. Electrospun fibers are featured by large surface area, high …
delivery of therapeutic agents. Electrospun fibers are featured by large surface area, high …
An overview of polymeric nanomicelles in clinical trials and on the market
X Zheng, J Xie, X Zhang, W Sun, H Zhao, Y Li… - Chinese Chemical …, 2021 - Elsevier
Polymeric nanomedicine is a promising and rapidly evolving field. Among the different
polymeric carriers, polymeric micelle (PM) with nanoscale size exhibit potent physical and …
polymeric carriers, polymeric micelle (PM) with nanoscale size exhibit potent physical and …
An update on actively targeted liposomes in advanced drug delivery to glioma
S Mojarad-Jabali, M Farshbaf, PR Walker… - International Journal of …, 2021 - Elsevier
High-grade glioma is one of the most aggressive types of cancer with a low survival rate
ranging from 12 to 15 months after the first diagnosis. Though being the most common …
ranging from 12 to 15 months after the first diagnosis. Though being the most common …
Self-assembled organic nanomaterials for drug delivery, bioimaging, and cancer therapy
Over the past few decades, tremendous progress has been made in the development of
engineering nanomaterials, which opened new horizons in the field of diagnosis and …
engineering nanomaterials, which opened new horizons in the field of diagnosis and …
Immune escape in glioblastoma multiforme and the adaptation of immunotherapies for treatment
JRD Pearson, S Cuzzubbo, S McArthur… - Frontiers in …, 2020 - frontiersin.org
Glioblastoma multiforme (GBM) is the most frequently occurring primary brain tumor and has
a very poor prognosis, with only around 5% of patients surviving for a period of 5 years or …
a very poor prognosis, with only around 5% of patients surviving for a period of 5 years or …
Recent advances in drug delivery systems for targeting brain tumors
Y Zhao, P Yue, Y Peng, Y Sun, X Chen, Z Zhao… - Drug delivery, 2023 - Taylor & Francis
Brain tumor accounts for about 1.6% of incidence and 2.5% of mortality of all tumors, and the
median survival for brain tumor patients is only about 20 months. The treatment for brain …
median survival for brain tumor patients is only about 20 months. The treatment for brain …
Facilitating the translation of nanomedicines to a clinical product: challenges and opportunities
V Agrahari, V Agrahari - Drug Discovery Today, 2018 - Elsevier
Highlights•Clinical translation and commercialization challenges of nanomedicine products.•
Manufacturing or scale-up, characterization, safety, stability and efficacy …
Manufacturing or scale-up, characterization, safety, stability and efficacy …
Nasal drug delivery of anticancer drugs for the treatment of glioblastoma: preclinical and clinical trials
FA Bruinsmann, G Richter Vaz… - Molecules, 2019 - mdpi.com
Glioblastoma (GBM) is the most lethal form of brain tumor, being characterized by the rapid
growth and invasion of the surrounding tissue. The current standard treatment for …
growth and invasion of the surrounding tissue. The current standard treatment for …
Nanoformulation properties, characterization, and behavior in complex biological matrices: Challenges and opportunities for brain-targeted drug delivery applications …
V Agrahari, PA Burnouf, T Burnouf… - Advanced Drug Delivery …, 2019 - Elsevier
Nanocarriers (synthetic/cell-based have attracted enormous interest for various therapeutic
indications, including neurodegenerative disorders. A broader understanding of the impact …
indications, including neurodegenerative disorders. A broader understanding of the impact …
A NIR-II-emitting gold nanocluster-based drug delivery system for smartphone-triggered photodynamic theranostics with rapid body clearance
Nanomedicine has grown structurally complex in order to perform multiple tasks at a time.
However, their unsatisfied reliability, uniformity and reproducibility account for the high rates …
However, their unsatisfied reliability, uniformity and reproducibility account for the high rates …