Purpose Osteoporotic fracture is the main complication of osteoporosis. The current
management is to discharge patients as early as possible so they can get back to their daily …

Osteoporosis is a systemic skeletal disorder characterized by bone loss, which leads to
impaired bone strength and an increased risk of fractures. Two million fractures are …

Objective To outline the efficacy and risks of bisphosphonate therapy for the management of
osteoporosis and describe which patients might be eligible for bisphosphonate “drug …

Objectives To identify and synthesise the best available evidence on the accuracy of the
currently available tools for predicting fracture risk. Methods We systematically searched …

Background Since screening programs identify only a small proportion of the population as
eligible for an intervention, genomic prediction of heritable risk factors could decrease the …

It is well recognized that bone loss accelerates in hypogonadal states, with female
menopause being the classic example of sex hormones affecting the regulation of bone …

This cohort study of 1,614 postmenopausal Japanese women followed for 6.7 years showed
that overweight/obesity and underweight are both risk factors for fractures at different sites …

Background Recent studies are lacking reports on mortality after non-hip fractures in adults
aged> 65. Methods This retrospective, matched-cohort study used de-identified health …

The risk of a recurrent fragility fracture is particularly high immediately following the fracture.
This study provides adjustments to FRAX-based fracture probabilities accounting for the site …

The use of FRAX, particularly in the absence of BMD, has been the subject of some debate
and is the focus of this review. The clinical risk factors used in FRAX have high validity as …