[HTML][HTML] Effect of P-glycoprotein (P-gp) inducers on exposure of P-gp substrates: review of clinical drug–drug interaction studies

M Elmeliegy, M Vourvahis, C Guo, DD Wang - Clinical pharmacokinetics, 2020 - Springer
Understanding transporter-mediated drug–drug interactions (DDIs) for investigational
agents is important during drug development to assess DDI liability, its clinical relevance …

Trends and targets in antiviral phototherapy

A Wiehe, JM O'Brien, MO Senge - Photochemical & Photobiological …, 2019 - pubs.rsc.org
Photodynamic therapy (PDT) is a well-established treatment option in the treatment of
certain cancerous and pre-cancerous lesions. Though best-known for its application in …

[HTML][HTML] The mechanism of microglia-mediated immune inflammation in ischemic stroke and the role of natural botanical components in regulating microglia: A review

J Zeng, T Bao, K Yang, X Zhu, S Wang… - Frontiers in …, 2023 - frontiersin.org
Ischemic stroke (IS) is one of the most fatal diseases. Neuroimmunity, inflammation, and
oxidative stress play important roles in various complex mechanisms of IS. In particular, the …

Clinical relevance of St. John's wort drug interactions revisited

S Nicolussi, J Drewe, V Butterweck… - British journal of …, 2020 - Wiley Online Library
The first clinically relevant reports of preparations of St. John's wort (SJW), a herbal medicine
with anti‐depressant effects, interacting with other drugs, altering their bioavailability and …

[HTML][HTML] Interactions between natural products and cancer treatments: Underlying mechanisms and clinical importance

WJJ Chan, J Adiwidjaja, AJ McLachlan… - Cancer chemotherapy …, 2023 - Springer
Natural products, also referred to as dietary supplements, complementary and alternative
medicines, and health or food supplements are widely used by people living with cancer …

[HTML][HTML] Pharmacokinetic interactions between herbal medicines and drugs: their mechanisms and clinical relevance

L Rombolà, D Scuteri, S Marilisa, C Watanabe… - Life, 2020 - mdpi.com
The therapeutic efficacy of a drug or its unexpected unwanted side effects may depend on
the concurrent use of a medicinal plant. In particular, constituents in the medicinal plant …

Ethnoracial health disparities and the ethnopsychopharmacology of psychedelic-assisted psychotherapies.

C Fogg, TI Michaels, S de la Salle… - Experimental and …, 2021 - psycnet.apa.org
Emerging evidence from randomized, double-blind, placebo-controlled clinical trials
suggests psychedelic compounds such as 3, 4-methylenedioxymethamphetamine (MDMA) …

Content variability of bioactive secondary metabolites in Hypericum perforatum L.

A Carrubba, S Lazzara, A Giovino, G Ruberto… - Phytochemistry …, 2021 - Elsevier
Abstract St John's Wort (Hypericum perforatum L.; Hypericaceae) is a perennial medicinal
herb widespread and largely used in folk medicine inside the Mediterranean basin. Many …

Hyperforin: A natural lead compound with multiple pharmacological activities

XX Li, Y Yan, J Zhang, K Ding, CY Xia, XG Pan, YJ Shi… - Phytochemistry, 2023 - Elsevier
Abstract Hypericum perforatum L.(Clusiaceae), commonly known as St. John's wort, has a
rich historical background as one of the oldest and most widely studied herbal medicines …

[HTML][HTML] Protective role of St. John's wort and its components hyperforin and hypericin against diabetes through inhibition of inflammatory signaling: Evidence from in …

M Novelli, P Masiello, P Beffy, M Menegazzi - International journal of …, 2020 - mdpi.com
Diabetes mellitus is a very common chronic disease with progressively increasing
prevalence. Besides the well-known autoimmune and inflammatory pathogenesis of type 1 …