Stroke is a serious neurological disease, and constitutes a major cause of death and
disability throughout the world. The pathophysiology of stroke is complex, and involves …

After ischaemic stroke, brain damage can be curtailed by rescuing the 'ischaemic penumbra'—
that is, the severely hypoperfused, at-risk but not yet infarcted tissue. Current evidence …

Neuroprotectant strategies that have worked in rodent models of stroke have failed to
provide protection in clinical trials. Here we show that the opposite circadian cycles in …

Oxygen treatment has been a cornerstone of acute medical care for numerous pathological
states. Initially, this was supported by the assumed need to avoid hypoxaemia and tissue …

Central nervous system (CNS) injuries, including stroke, traumatic brain injury, and spinal
cord injury, are leading causes of long-term disability. It is estimated that more than half of …

Background: Previous studies have shown that hyperbaric oxygen therapy (HBOT) can
improve the motor functions and memory of post-stroke patients in the chronic stage …

Introduction Generally, nursing interventions during the acute stages following a stroke aim
at preventing secondary brain injury (intracranial hypertension), maintaining the airways …

Background and Purpose—Prolonged ischemia causes blood–brain barrier (BBB) damage
and increases the incidence of neurovasculature complications secondary to reperfusion …

Neuronal activity in the brain depends on mostly aerobic generation of energy equivalents
and thus on a constant O 2 supply. Oxygenation of the vertebrate brain has been optimized …

Michalski D, Härtig W, Schneider D, Hobohm C. Use of normobaric and hyperbaric oxygen
in acute focal cerebral ischemia–a preclinical and clinical review. Acta Neurol Scand: 2011 …