Light sheet fluorescence microscopy

EHK Stelzer, F Strobl, BJ Chang, F Preusser… - Nature Reviews …, 2021 - nature.com
Light sheet fluorescence microscopy (LSFM) uses a thin sheet of light to excite only
fluorophores within the focal volume. Light sheet microscopes (LSMs) have a true optical …

How to turn an organism into a model organism in 10 'easy'steps

BJ Matthews, LB Vosshall - Journal of Experimental Biology, 2020 - journals.biologists.com
Many of the major biological discoveries of the 20th century were made using just six
species: Escherichia coli bacteria, Saccharomyces cerevisiae and Schizosaccharomyces …

Neurochemical organization of the Drosophila brain visualized by endogenously tagged neurotransmitter receptors

S Kondo, T Takahashi, N Yamagata, Y Imanishi… - Cell Reports, 2020 - cell.com
Neurotransmitters often have multiple receptors that induce distinct responses in receiving
cells. Expression and localization of neurotransmitter receptors in individual neurons are …

Cell types and neuronal circuitry underlying female aggression in Drosophila

CE Schretter, Y Aso, AA Robie, M Dreher, MJ Dolan… - Elife, 2020 - elifesciences.org
Aggressive social interactions are used to compete for limited resources and are regulated
by complex sensory cues and the organism's internal state. While both sexes exhibit …

[HTML][HTML] Context-dependent control of behavior in Drosophila

TB Oram, GM Card - Current Opinion in Neurobiology, 2022 - Elsevier
The representation of contextual information peripheral to a salient stimulus is central to an
animal's ability to correctly interpret and flexibly respond to that stimulus. While the …

Drosophila voltage-gated sodium channels are only expressed in active neurons and are localized to distal axonal initial segment-like domains

TA Ravenscroft, J Janssens, PT Lee… - Journal of …, 2020 - Soc Neuroscience
In multipolar vertebrate neurons, action potentials (APs) initiate close to the soma, at the
axonal initial segment. Invertebrate neurons are typically unipolar with dendrites integrating …

Imaging flies by fluorescence microscopy: principles, technologies, and applications

S Dunst, P Tomancak - Genetics, 2019 - academic.oup.com
The development of fluorescent labels and powerful imaging technologies in the last two
decades has revolutionized the field of fluorescence microscopy, which is now widely used …

A spatially dynamic network underlies the generation of inspiratory behaviors

NA Baertsch, LJ Severs… - Proceedings of the …, 2019 - National Acad Sciences
The ability of neuronal networks to reconfigure is a key property underlying behavioral
flexibility. Networks with recurrent topology are particularly prone to reconfiguration through …

Amyotrophic lateral sclerosis: proteins, proteostasis, prions, and promises

L McAlary, YL Chew, JS Lum, NJ Geraghty… - Frontiers in Cellular …, 2020 - frontiersin.org
Amyotrophic lateral sclerosis (ALS) is characterized by the progressive degeneration of the
motor neurons that innervate muscle, resulting in gradual paralysis and culminating in the …

Bioelectric regulation of intestinal stem cells

A Petsakou, N Perrimon - Trends in cell biology, 2023 - cell.com
Proper regulation of ion balance across the intestinal epithelium is essential for
physiological functions, while ion imbalance causes intestinal disorders with dire health …