Metabolomics generates a profile of small molecules that are derived from cellular
metabolism and can directly reflect the outcome of complex networks of biochemical …

The life sciences are currently being transformed by an unprecedented wave of
developments in molecular analysis, which include important advances in instrumental …

Objective It is evident that the gut microbiota and factors that influence its composition and
activity effect human metabolic, immunological and developmental processes. We …

Urine metabolomics is widely used for biomarker research in the fields of medicine and
toxicology. As a consequence, characterization of the variations of the urine metabolome …

Background & Aims Studies in mice have shown that the intestinal microbiota can contribute
to obesity via the anorexigenic gut hormone glucagon-like peptide 1 (GLP1) and bile acids …

Inflammatory bowel disease (IBD) is a chronic inflammatory disease of the gastrointestinal
tract of uncertain origin, which includes ulcerative colitis (UC) and Crohn's disease (CD) …

Objective Faecal microbiota transplant (FMT) effectively treats recurrent Clostridioides
difficile infection (rCDI), but its mechanisms of action remain poorly defined. Certain bile …

BACKGROUND: Primary sclerosing cholangitis (PSC) is a cholestatic liver disease with no
effective medical therapies. A perturbation of the gut microbiota has been described in …

Metabolomics is a rapidly advancing field, and much of our understanding of the subject has
come from research on cell lines. However, the results and interpretation of such studies …

To reveal metabolomic changes caused by a biological event in quantitative metabolomics,
it is critical to use an analytical tool that can perform accurate and precise quantification to …