Atopic dermatitis: new insights and opportunities for therapeutic intervention

DYM Leung - Journal of Allergy and Clinical Immunology, 2000 - Elsevier
Atopic dermatitis (AD) is a chronic inflammatory skin disease that frequently predates the
development of allergic rhinitis or asthma. It is an important skin condition with significant …

[HTML][HTML] Manipulation of innate and adaptive immunity by staphylococcal superantigens

SW Tuffs, SMM Haeryfar, JK McCormick - Pathogens, 2018 - mdpi.com
Staphylococcal superantigens (SAgs) constitute a family of potent exotoxins secreted by
Staphylococcus aureus and other select staphylococcal species. SAgs function to cross-link …

[PDF][PDF] Staphylococcus aureus enterotoxins: a key in airway disease?

C Bachert, P Gevaert, P Van Cauwenberge - Allergy, 2002 - academia.edu
Staphylococcus aureus (S. aureus), one of three pathogenic species of the Gram-positive
cocci, is often found as part of the normal microflora of the human skin, the upper respiratory …

Superantigens and nasal polyps

C Bachert, T Van Zele, P Gevaert… - Current allergy and …, 2003 - Springer
Nasal polyps represent an often severe T-cell-orchestrated eosinophilic upper airway
disease with currently unknown pathogenesis, often associated with lower airway disease …

Staphylococcal alpha-toxin is a strong inducer of interleukin-17 in humans

M Niebuhr, M Gathmann, H Scharonow… - Infection and …, 2011 - Am Soc Microbiol
Patients with atopic dermatitis (AD) are frequently colonized with Staphylococcus aureus,
with one-third of isolates producing alpha-toxin. Moreover, S. aureus colonization is …

Staphylococcus aureus superantigens and airway disease

C Bachert, P Gevaert, P Cauwenberge - Current allergy and asthma …, 2002 - Springer
Twenty-five percent of the population are permanent carriers of Staphylococcus aureus,
possibly producing a variety of toxins with superantigenic properties. Staphylococcal …

[HTML][HTML] Staphylococcus Aureus in chronic airway diseases: An overview

M Flora, F Perrotta, A Nicolai, R Maffucci, A Pratillo… - Respiratory …, 2019 - Elsevier
This review investigates about the role of Staphylococcus Aureus (S. aureus) and S. aureus
enterotoxins (SEs) in the pathogenesis of several chronic airway diseases. S. aureus is part …

Alpha‐toxin is produced by skin colonizing Staphylococcus aureus and induces a T helper type 1 response in atopic dermatitis

K Breuer, M Wittmann, K Kempe, A Kapp… - Clinical & …, 2005 - Wiley Online Library
Background Staphylococcus aureus is a well known trigger factor of atopic dermatitis (AD).
Besides the superantigens, further exotoxins are produced by S. aureus and may have an …

Role of IL-12 receptor β1 in regulation of T cell response by APC in experimental autoimmune encephalomyelitis

GX Zhang, S Yu, B Gran, J Li, I Siglienti… - The Journal of …, 2003 - journals.aai.org
IL-12 was thought to be involved in the development of experimental autoimmune
encephalomyelitis (EAE), a Th1 cell-mediated autoimmune disorder of the CNS. However …

[HTML][HTML] Dietary plasma protein supplements prevent the release of mucosal proinflammatory mediators in intestinal inflammation in rats

A Pérez-Bosque, L Miró, J Polo, L Russell… - The Journal of …, 2010 - Elsevier
Spray-dried plasma (SDP) is a complex mixture of active proteins that modulates the
immune response of gut-associated lymphoid tissue. We examined whether SDP and Ig …