Feasibility of cardiovascular magnetic resonance to detect oxygenation deficits in patients with multi-vessel coronary artery disease triggered by breathing maneuvers

K Fischer, K Yamaji, S Luescher, Y Ueki, B Jung… - Journal of …, 2018 - Springer
Background Hyperventilation with a subsequent breath-hold has been successfully used as
a non-pharmacological vasoactive stimulus to induce changes in myocardial oxygenation …

The blood oxygen level dependent (BOLD) effect of in-vitro myoglobin and hemoglobin

DP Guensch, MC Michel, SP Huettenmoser, B Jung… - Scientific reports, 2021 - nature.com
The presence of deoxygenated hemoglobin (Hb) results in a drop in T2 and T2* in magnetic
resonance imaging (MRI), known as the blood oxygenation level-dependent (BOLD-) effect …

NIH workshop 2018: towards minimally invasive or noninvasive approaches to assess tissue oxygenation Pre-and Post-transfusion

MJ Ochocinska, SL Spitalnik, A Abuhamad… - Transfusion medicine …, 2021 - Elsevier
Because blood transfusion is one of the most common therapeutic interventions in
hospitalized patients, much recent research has focused on improving the storage quality in …

[HTML][HTML] Individual differences in haemoglobin concentration influence bold fMRI functional connectivity and its correlation with cognition

PGD Ward, ER Orchard, S Oldham, A Arnatkevičiūtė… - NeuroImage, 2020 - Elsevier
Resting-state connectivity measures the temporal coherence of the spontaneous neural
activity of spatially distinct regions, and is commonly measured using BOLD-fMRI. The BOLD …

Oxygenation-sensitive cardiac MRI with vasoactive breathing maneuvers for the non-invasive assessment of coronary microvascular dysfunction

E Hillier, J Covone, MG Friedrich - JoVE (Journal of Visualized …, 2022 - jove.com
Oxygenation-sensitive cardiac magnetic resonance imaging (OS-CMR) is a diagnostic
technique that uses the inherent paramagnetic properties of deoxyhemoglobin as an …

Relationship between myocardial oxygenation and blood pressure: Experimental validation using oxygenation-sensitive cardiovascular magnetic resonance

DP Guensch, K Fischer, C Jung, S Hurni, BM Winkler… - PLoS …, 2019 - journals.plos.org
Background The relationship between mean arterial pressure (MAP) and coronary blood
flow is well described. There is autoregulation within a MAP range of 60 to 140 mmHg …

Hyperventilation-induced heart rate response as a potential marker for cardiovascular disease

SM Hawkins, DP Guensch, MG Friedrich, G Vinco… - Scientific reports, 2019 - nature.com
An increase of heart rate to physical or mental stress reflects the ability of the autonomous
nervous system and the heart to respond adequately. Hyperventilation is a user-controlled …

Myocardial T2* Mapping with Ultrahigh Field Magnetic Resonance: Physics and Frontier Applications

T Huelnhagen, K Paul, MC Ku, T Serradas Duarte… - Frontiers in …, 2017 - frontiersin.org
Cardiovascular magnetic resonance imaging (CMR) has become an indispensable clinical
tool for the assessment of morphology, function and structure of the heart muscle. By …

Introducing a free-breathing MRI method to assess peri-operative myocardial oxygenation and function: A volunteer cohort study

DP Guensch, CD Utz, B Jung, S Dozio… - European Journal of …, 2024 - journals.lww.com
BACKGROUND Induction of general anaesthesia has many potential triggers for peri-
operative myocardial ischaemia including the acute disturbance of blood gases that …

Reduced deep regional cerebral venous oxygen saturation in hemodialysis patients using quantitative susceptibility mapping

C Chai, S Liu, L Fan, L Liu, J Li, C Zuo, T Qian… - Metabolic Brain …, 2018 - Springer
Cerebral venous oxygen saturation (SvO 2) is an important indicator of brain function. There
was debate about lower cerebral oxygen metabolism in hemodialysis patients and there …