Metastatic non-small cell lung cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

D Planchard, ST Popat, K Kerr, S Novello… - Annals of …, 2018 - annalsofoncology.org
Primary lung cancer remains the most common malignancy after non-melanocytic skin
cancer, and deaths from lung cancer exceed those from any other malignancy worldwide [1] …

Emerging strategies to target RAS signaling in human cancer therapy

K Chen, Y Zhang, L Qian, P Wang - Journal of hematology & oncology, 2021 - Springer
Abstract RAS mutations (HRAS, NRAS, and KRAS) are among the most common
oncogenes, and around 19% of patients with cancer harbor RAS mutations. Cells harboring …

Non–small cell lung cancer, version 5.2017, NCCN clinical practice guidelines in oncology

DS Ettinger, DE Wood, DL Aisner, W Akerley… - Journal of the National …, 2017 - jnccn.org
This selection from the NCCN Guidelines for Non–Small Cell Lung Cancer (NSCLC)
focuses on targeted therapies and immunotherapies for metastatic NSCLC, because …

Comparing and contrasting predictive biomarkers for immunotherapy and targeted therapy of NSCLC

DR Camidge, RC Doebele, KM Kerr - Nature reviews Clinical oncology, 2019 - nature.com
The era of personalized medicine for advanced-stage non-small-cell lung cancer (NSCLC)
began when biomarker-based evidence of molecular pathway and/or oncogene addiction of …

[HTML][HTML] Nivolumab versus docetaxel in advanced nonsquamous non–small-cell lung cancer

H Borghaei, L Paz-Ares, L Horn… - … England Journal of …, 2015 - Mass Medical Soc
Background Nivolumab, a fully human IgG4 programmed death 1 (PD-1) immune-
checkpoint–inhibitor antibody, disrupts PD-1–mediated signaling and may restore antitumor …

Metastatic non-small-cell lung cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

S Novello, F Barlesi, R Califano, T Cufer… - Annals of …, 2016 - annalsofoncology.org
Primary lung cancer remains the most common malignancy after non-melanocytic skin
cancer, and deaths from lung cancer exceed those from any other malignancy worldwide [1] …

Correction to:“Metastatic non-small cell lung cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up”

D Planchard, S Popat, K Kerr, S Novello… - Annals of …, 2019 - annalsofoncology.org
1. In KEYNOTE-189, patients with metastatic non-squamous NSCLC, PS 0-1, without
sensitising EGFR or ALK mutations, were randomised to receive pemetrexed and a platinum …

[HTML][HTML] Pan-Asian adapted Clinical Practice Guidelines for the management of patients with metastatic non-small-cell lung cancer: a CSCO–ESMO initiative endorsed …

YL Wu, D Planchard, S Lu, H Sun, N Yamamoto… - Annals of …, 2019 - Elsevier
The most recent version of the European Society for Medical Oncology (ESMO) Clinical
Practice Guidelines for the diagnosis, treatment and follow-up of metastatic non-small-cell …

KRAS oncogene in non-small cell lung cancer: clinical perspectives on the treatment of an old target

M Román, I Baraibar, I López, E Nadal, C Rolfo… - Molecular cancer, 2018 - Springer
Lung neoplasms are the leading cause of death by cancer worldwide. Non-small cell lung
cancer (NSCLC) constitutes more than 80% of all lung malignancies and the majority of …

Ramucirumab plus docetaxel versus placebo plus docetaxel for second-line treatment of stage IV non-small-cell lung cancer after disease progression on platinum …

EB Garon, TE Ciuleanu, O Arrieta, K Prabhash… - The Lancet, 2014 - thelancet.com
Background Ramucirumab is a human IgG1 monoclonal antibody that targets the
extracellular domain of VEGFR-2. We aimed to assess efficacy and safety of treatment with …