Ketamine, a racemic mixture consisting of (S)-and (R)-ketamine, has been in clinical use
since 1970. Although best characterized for its dissociative anesthetic properties, ketamine …

Hikikomori, a severe form of social withdrawal, has long been observed in Japan mainly
among youth and adolescents since around the 1970s, and has been especially highlighted …

Background Previous research has investigated the efficacy of clozapine in reducing
suicidality in patients with schizophrenia and schizoaffective disorder. We aimed to …

Importance Countering depressive disorders is a public health priority. Currently,
antidepressants are the first-line treatment, although they show modest effects. In men …

Traditional pharmacological treatments for depression have a delayed therapeutic onset,
ranging from several weeks to months, and there is a high percentage of individuals who …

Regulation of emotions is generally associated exclusively with the brain. However, there is
evidence that peripheral systems are also involved in mood, stress vulnerability vs …

Despite the continuous advancement in neurosciences as well as in the knowledge of
human behaviors pathophysiology, currently suicide represents a puzzling challenge. The …

Testosterone plays a pivotal role in maintaining balance within the multi‐dimensional
psychological network of mood, behaviour, self‐perception and perceived quality of life in …

Background: More than 2% of the general population experience suicidal ideas each year
and a large number of them will attempt suicide. Evidence-based therapeutic options to …

Abstract Lower Urinary Tract Symptoms (LUTS) are frequently present in the general
population as patients age with approximately a third of individuals experiencing LUTS …