Objective Emerging pathological evidence suggests that there is an association between
glymphatic dysfunction and the progression of Parkinson's disease (PD). However, the …

Parkinson's disease (PD) is the second most common neurodegenerative disorder of the
elderly, presenting primarily with symptoms of motor impairment. The disease is diagnosed …

In recent years, an emerging body of evidence has forged links between Parkinson's
disease (PD) and type 2 diabetes mellitus (T2DM). In observational studies, those with …

Although nanomedicine have greatly developed and human life span has been extended,
we have witnessed the soared incidence of central nervous system (CNS) diseases …

RESUMO A doença de Parkinson é a segunda doença neurodegenerativa mais comum,
tendo sido documentado um aumento significativo da sua prevalência nas últimas três …

Neurodegenerative diseases (NDs) result from progressive deterioration of selectively
susceptible neuron populations in different central nervous system (CNS) regions. NDs are …

There is evidence from observational studies for a role of a number of environmental
exposures and lifestyle habits in modulating the risk for Parkinson's disease. Environmental …

The increase in human life expectancy has become a challenge to reduce the deleterious
consequences of aging. Nowadays, an increasing number of the population suffer from age …

Parkinson's disease (PD) is the second most common neurodegenerative disease and is
characterized by dopaminergic neuronal loss. The exact pathogenesis of PD is complex and …

The failure rate for the translation of drugs from animal testing to human treatments remains
at over 92%, where it has been for the past few decades. The majority of these failures are …