Compendium of naringenin: Potential sources, analytical aspects, chemistry, nutraceutical potentials and pharmacological profile

S Singh, A Sharma, V Monga… - Critical Reviews in Food …, 2023 - Taylor & Francis
Naringenin is flavorless, water insoluble active principle belonging to flavanone subclass. It
exhibits a diverse pharmacological profile as well as divine nutraceutical values. Although …

[HTML][HTML] An overview of herbal-based antidiabetic drug delivery systems: Focus on lipid-and inorganic-based nanoformulations

EK Kambale, J Quetin-Leclercq, PB Memvanga… - Pharmaceutics, 2022 - mdpi.com
Diabetes is a metabolic pathology with chronic high blood glucose levels that occurs when
the pancreas does not produce enough insulin or the body does not properly use the insulin …

Soluplus® as a solubilizing excipient for poorly water-soluble drugs: recent advances in formulation strategies and pharmaceutical product features

MS Attia, A Elshahat, A Hamdy, AM Fathi… - Journal of Drug Delivery …, 2023 - Elsevier
Since the emergence of Soluplus®(SOL) as a commercial graft copolymer, several
publications have been issued on its promising potential as a solubilizing excipient that …

[HTML][HTML] Nanocarriers for delivery of siRNA as gene silencing mediator

A Morales-Becerril, L Aranda-Lara, K Isaac-Olivé… - EXCLI …, 2022 - ncbi.nlm.nih.gov
The term nanocarrier refers to sub-micrometric particles of less than 100 nm, designed to
transport, distribute, and release nanotechnology-based drug delivery systems. siRNA …

Novel strategies to oral delivery of insulin: Current progress of nanocarriers for diabetes management

A Abdel‐Moneim, H Ramadan - Drug Development Research, 2022 - Wiley Online Library
Diabetes mellitus is one of the most serious public health problems in the world. Repeated
daily injections of subcutaneous insulin is the standard treatment for patients with type 1 …

[HTML][HTML] Development of a Multifunctional Oral Dosage Form via Integration of Solid Dispersion Technology with a Black Seed Oil-Based Self-Nanoemulsifying Drug …

AY Sherif, AAW Shahba - Biomedicines, 2023 - mdpi.com
Lansoprazole (LZP) is used to treat acid-related gastrointestinal disorders; however, its low
aqueous solubility limits its oral absorption. Black seed oil (BSO) has gastroprotective …

[HTML][HTML] Formulation and evaluation of SNEDDS loaded with original lipophenol for the oral route to prevent dry AMD and Stragardt's disease

M Vincent, L Simon, P Brabet, P Legrand, C Dorandeu… - Pharmaceutics, 2022 - mdpi.com
Dry age-related macular degeneration (Dry AMD) and Stargardt's disease (STGD1) are
common eye diseases, characterized by oxidative and carbonyl stress (COS)-inducing …

[HTML][HTML] A Quality by design paradigm for albumin-based nanoparticles: formulation optimization and enhancement of the antitumor activity

MHS Dawoud, A Abdel-Daim, MS Nour… - Journal of …, 2023 - Springer
Purpose Albumin nanoparticles are promising carriers for therapeutic agents, owing to their
biocompatibility, safety, and versatility in fabrication. The formulation of albumin …

The chimera of TPGS and nanoscale lipid carriers as lymphatic drug delivery vehicles to fight metastatic cancers

AY Sherif, GI Harisa, FK Alanazi - Current Drug Delivery, 2024 - ingentaconnect.com
The lymphatic system (LS) plays a crucial role in fluid balance, transportation of
macromolecules, and immune response. Moreover, LS is a channel for microbial invasion …

[PDF][PDF] SNEDDS as lipid-based nanocarrier systems: concepts and formulation insights

LD Gottemukkula, S Sampathi - Int J App Pharm, 2022 - academia.edu
Approximately 40% of newly discovered chemical entities have low solubility and possess
low bioavailability after oral administration. Lipid-based drug delivery systems (LBDDS) …