Human leukocyte antigen (HLA) encoded by the HLA gene is an important modulator for
immune responses and drug hypersensitivity reactions as well. Genetic polymorphisms of …

Pharmacogenomics can enhance patient care by enabling treatments tailored to genetic
make-up and lowering risk of serious adverse events. As of June 2019, there are 132 …

Response to a drug often differs widely among individual patients. This variability is
frequently observed not only with respect to effective responses but also with adverse drug …

Background The use of pharmacogenomic testing in the clinical setting has the potential to
improve the safety and effectiveness of drug therapy, yet studies have revealed that …

Increasing enthusiasm for clinical pharmacogenetic testing and the availability of
pharmacogenetic-based guidelines indicate that pediatricians will increasingly be expected …

Background Pharmacogenetics practice has been successfully implemented in many
developed countries to enhance personalized medicine and improve clinical and economic …

Purpose The development and implementation of a multidisciplinary pharmacogenomics
clinic within the framework of an established community-based medical genetics program …

Pharmacists are uniquely qualified to play essential roles in the clinical implementation of
pharmacogenomics. However, specific responsibilities and resources needed for these …

The number of clinically relevant gene‐based guidelines and recommendations pertaining
to drug prescribing continues to grow. Incorporating gene–drug interaction information into …

While recent discoveries have paved the way for the use of genotype-guided prescribing in
some clinical environments, significant debate persists among clinicians and researchers …