Mechanisms of action of non-enzymatic antioxidants to control oxidative stress during in vitro follicle growth, oocyte maturation, and embryo development

BR Silva, JRV Silva - Animal reproduction science, 2023 - Elsevier
In vitro follicle growth and oocyte maturation still has a series of limitations, since not all
oocytes matured in vitro have the potential to develop in viable embryos. One of the factors …

Challenges and considerations during in vitro production of porcine embryos

PR Chen, BK Redel, KC Kerns, LD Spate, RS Prather - Cells, 2021 - mdpi.com
Genetically modified pigs have become valuable tools for generating advances in animal
agriculture and human medicine. Importantly, in vitro production and manipulation of …

NRF2 attenuation aggravates detrimental consequences of metabolic stress on cultured porcine parthenote embryos

WG Glanzner, LR da Silva Sousa, K Gutierrez… - Scientific Reports, 2024 - nature.com
The nuclear factor erythroid 2–related factor 2 (NRF2) is a crucial transcription factor that
plays a central role in regulating oxidative stress pathways by binding antioxidant response …

Cumulus cell and oocyte gene expression in prepubertal gilts and sows identifies cumulus cells as a prime informative parameter of oocyte quality

LM Haug, RC Wilson, AH Gaustad, R Jochems… - Biology, 2023 - mdpi.com
Simple Summary Progress has been made in pig in vitro embryo production (IVEP) over the
years, but some of the remaining challenges are low embryo production rates compared to …

Cumulus‐oocyte complexes from sows show differences in lipid metabolism compared to cumulus‐oocyte complexes from prepubertal gilts during in vitro maturation

TCF Silva, MAN Dode, TF Braga… - Molecular …, 2023 - Wiley Online Library
This study aimed to evaluate the effects of donor age on lipid metabolism during in vitro
maturation (IVM) of pigs cumulus‐oocyte complexes (COCs). We evaluated transcript levels …

Importance of lipid metabolism on oocyte maturation and early embryo development: Can we apply what we know to buffalo?

DFD Marin, NN da Costa, PPB Santana… - Animal reproduction …, 2019 - Elsevier
The knowledge about the biological events that regulate lipid metabolism in oocytes and
embryos in buffalo is scarce. Lipogenesis, lipolysis, transport and oxidation of fatty acids …

L-carnitine supplementation during in vitro maturation and in vitro culture does not affect the survival rates after vitrification and warming but alters Inf-T and ptgs2 gene …

DF Carrillo-González, N Rodríguez-Osorio… - International Journal of …, 2020 - mdpi.com
l-carnitine is a potent antioxidant used for in vitro culture systems. Controversial results have
been reported using l-carnitine in culture medium at different stages of in vitro bovine …

Metabolites secreted by bovine embryos in vitro predict pregnancies that the recipient plasma metabolome cannot, and vice versa

E Gomez, N Canela, P Herrero, A Cereto, I Gimeno… - Metabolites, 2021 - mdpi.com
This work describes the use of mass spectrometry-based metabolomics as a non-invasive
approach to accurately predict birth prior to embryo transfer (ET) starting from embryo culture …

[HTML][HTML] Importance of Supplementation during In Vitro Production of Livestock Animals

L Nemcova, AR Bartkova, V Kinterova, T Toralova - 2023 - intechopen.com
Increasing infertility is one of the most serious health problems of today. Over the past few
years, we have had the opportunity to follow the progress of technologies focused on the …

Impact of reducing lipid content during in vitro embryo production: A systematic review and meta-analysis

EM Vasconcelos, RF Braga, GR Leal, RPR Carvalho… - Theriogenology, 2024 - Elsevier
There is still no consensus regarding the role of lipid modulators during in vitro embryo
production. Thus, we investigated how lipid reducers during the in vitro maturation of …