Depression is one of the key conditions addressed by the Mental Health Gap Action
Programme (mhGAP) of WHO that can lead to self-harm and suicide. Depression is …

Candidates generated from unsaturated ketone (chalcone) demonstrated as strong,
reversible and specific monoamine oxidase-B (MAO-B) inhibitory activity. For the research …

Sixteen compounds (TR1–TR16) were synthesized and evaluated for their inhibitory
activities against monoamine oxidase A and B (MAOs). Most of the derivatives showed …

Monoamine oxidase-B (MAO-B), acetylcholinesterase (AChE), and butyrylcholinesterase
(BChE) have been considered target enzymes of depression and neurodegenerative …

The current report provides an overview of the rapidly developing class of pyrazolines
having a benzothiazole moiety at N1. The synthetic approaches (mainly through the [3+ 2] …

We presented a general approach for synthesizing isoxazole-containing pyrazolines and
pyrazoles. The protocol involved [3+ 2] cycloaddition of the in situ generated nitrile imines …

The flavoenzyme monoamine oxidases (MAOs) are present in the mitochondrial outer
membrane and are responsible for the metabolism of biogenic amines. MAO deamination of …

Aim: To investigate the efficacy of exosome-like nanovesicles from citrus lemon (EXO-CLs)
in combating oxidative stress associated with Alzheimer's disease. Materials & methods …

Nine morpholine-derived halogenated chalcone derivatives (MHC1-MHC9) were
synthesized, and their inhibitory activity against monoamine oxidase (MAO) was evaluated …

Among the many reports published on strategies applicable to synthesizing pyrazolines and
its analogs, The 1, 3-dipolar cycloaddition offers a remarkably wide range of utility. Many 1, 3 …