Molecular oxygen (O2) is essential for most biological reactions in mammalian cells. When
the intracellular oxygen content decreases, it is called hypoxia. The process of hypoxia is …

Cell-matrix interactions play a critical role in tissue repair and regeneration. With gradual
uncovering of substrate mechanical characteristics that can affect cell-matrix interactions …

Biomimetic scaffolds supporting tissue regeneration are complex materials with
multifunctional characteristics. The unique biocompatibility and biodegradability of …

Background Low bone mineral density (LBMD), including osteoporosis and low bone mass,
has becoming a serious public health concern. We aimed to estimate the disease burden of …

Osteoporosis is a common metabolic bone disease, influenced by genetic and
environmental factors, that increases bone fragility and fracture risk and, therefore, has a …

Background Recently, the association between inflammatory bowel disease (including
ulcerative colitis and Crohn's disease) and BMD has attracted great interest in the research …

For bone defect repair under co-morbidity conditions, the use of biomaterials that can be non-
invasively regulated is highly desirable to avoid further complications and to promote …

Current solutions developed for the purpose of in and on body (IOB) electrical stimulation
(ES) lack autonomous qualities necessary for comfortable, practical, and self‐dependent …

ROS are highly reactive molecules which consist of a number of diverse chemical species,
including radical and non-radical oxygen species. Oxidative stress occurs as a result of an …

Hydroxyapatite (HA) is widely used in bone tissue engineering for its bioactivity and
biocompatibility, and a growing number of researchers are exploring ways to improve the …