Despite the overwhelming success of vaccines in preventing infectious diseases, there
remain numerous globally devastating diseases without fully protective vaccines, particularly …

Pulmonary diseases due to mycobacteria cause significant morbidity and mortality to human
health. In addition to tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), recent …

Tuberculosis (TB), caused by Mycobacterium tuberculosis (MTB), is a prevalent global
infectious disease and a leading cause of mortality worldwide. Currently, the only available …

Tuberculosis is the leading infectious disease killer globally due to a single pathogen.
Despite wide deployment of standard drug regimens, modern diagnostics and a vaccine …

Among infectious diseases, tuberculosis is the leading cause of death worldwide, and
represents a serious threat, especially in developing countries. The protective effects of …

Nations' ongoing struggles with a number of novel and reemerging infectious diseases,
including the ongoing global health issue, the SARS-Co-V2 (severe acute respiratory …

In addition to antibiotics, vaccination is considered among the most efficacious methods in
the control and the potential eradication of infectious diseases. New safe and effective …

The tuberculosis (TB) vaccine Bacillus Calmette‐Guérin (BCG) was introduced 100 years
ago, but as it provides insufficient protection against TB disease, especially in adults, new …

To fight tuberculosis, better vaccination strategies are needed. Live attenuated
Mycobacterium tuberculosis-derived vaccine, MTBVAC, is a promising candidate in the …

Polyclonal infections occur when at least two unrelated strains of the same pathogen are
detected in an individual. This has been linked to worse clinical outcomes in tuberculosis, as …