pathfindR: an R package for comprehensive identification of enriched pathways in omics data through active subnetworks

E Ulgen, O Ozisik, OU Sezerman - Frontiers in genetics, 2019 - frontiersin.org
Pathway analysis is often the first choice for studying the mechanisms underlying a
phenotype. However, conventional methods for pathway analysis do not take into account …

Data analysis methods for defining biomarkers from omics data

C Li, Z Gao, B Su, G Xu, X Lin - Analytical and Bioanalytical Chemistry, 2022 - Springer
Omics mainly includes genomics, epigenomics, transcriptomics, proteomics and
metabolomics. The rapid development of omics technology has opened up new ways to …

Incorporating pathway information into feature selection towards better performed gene signatures

S Tian, C Wang, B Wang - BioMed research international, 2019 - Wiley Online Library
To analyze gene expression data with sophisticated grouping structures and to extract
hidden patterns from such data, feature selection is of critical importance. It is well known …

pathfindR: an R package for pathway enrichment analysis utilizing active subnetworks

E Ulgen, O Ozisik, OU Sezerman - BioRxiv, 2018 - biorxiv.org
PathfindR is a tool for pathway enrichment analysis utilizing active subnetworks. It identifies
gene sets that form active subnetworks in a protein-protein interaction network using a list of …

NBIA: a network-based integrative analysis framework–applied to pathway analysis

T Nguyen, A Shafi, TM Nguyen, AG Schissler… - Scientific reports, 2020 - nature.com
With the explosion of high-throughput data, effective integrative analyses are needed to
decipher the knowledge accumulated in biological databases. Existing meta-analysis …

Biomolecular databases and subnetwork identification approaches of interest to big data community: an expert review

O Al-Harazi, A El Allali, D Colak - Omics: a journal of integrative …, 2019 - liebertpub.com
Next-generation sequencing approaches and genome-wide studies have become essential
for characterizing the mechanisms of human diseases. Consequently, many researchers …

Gene expression dataset classification using artificial neural network and clustering-based feature selection

AM Mabu, R Prasad, R Yadav - International Journal of Swarm …, 2020 - igi-global.com
With the progression of bioinformatics, applications of GE profiles on cancer diagnosis along
with classification have become an intriguing subject in the bioinformatics field. It holds …

Popbic: pathway-based order preserving biclustering algorithm towards the analysis of gene expression data

K Mandal, R Sarmah… - IEEE/ACM Transactions …, 2020 - ieeexplore.ieee.org
To understand the underlying biological mechanisms of gene expression data, it is important
to discover the groups of genes that have similar expression patterns under certain subsets …

[PDF][PDF] Identification of Lung Cancer Related Genes Using Enhanced Floyd Warshall Algorithm in a Protein to Protein Interaction Network.

AK Patil, SS Patil, P Manickam - International Journal of Intelligent …, 2018 - inass.org
Lung cancer is defined as an uncontrolled cell growing in the tissues of lung, which is also
said to be lung tumor. The lung cancer is curable in the starting stage, but identifying the …

Feature selection in GSNFS-based marker identification

S Kozuevanich, JH Chan, A Meechai - Proceedings of the Tenth …, 2019 - dl.acm.org
Gene Sub-Network-based Feature Selection (GSNFS) is a method capable of handling case-
control and multiclass studies for gene sub-network biomarker identification by an integrated …