Although great advances in elucidating the molecular basis and pathogenesis of
Alzheimer's disease (AD) have been made and multifarious novel therapeutic approaches …

Drug addiction is a chronically relapsing disorder that has been characterized by (1)
compulsion to seek and take the drug,(2) loss of control in limiting intake, and (3) emergence …

The neurotransmitter transporters (NTTs) belonging to the solute carrier 6 (SLC6) gene
family (also referred to as the neurotransmitter-sodium-symporter family or Na+/Cl …

The fundamental principle that unites addictive drugs appears to be that each enhances
synaptic dopamine by means that dissociate it from normal behavioral control, so that they …

Conditioned place preference (CPP) continues to be one of the most popular models to
study the motivational effects of drugs and non‐drug treatments in experimental animals …

Depression is a common mental disorder. The standard medical treatment is the selective
serotonin reuptake inhibitors (SSRIs). All characterized SSRIs are competitive inhibitors of …

Addiction is a disease of altered behavior. Addicts use drugs compulsively and will continue
to do so despite negative consequences. Even after prolonged periods of abstinence …

In our target article, we proposed that addiction could be envisioned as misperformance of a
decision-making machinery described by two systems (deliberative and habit systems) …

Drug-evoked synaptic plasticity is observed at many synapses and may underlie
behavioural adaptations in addiction. Mechanistic investigations start with the identification …

The SLC6 family of secondary active transporters are integral membrane solute carrier
proteins characterized by the Na+-dependent translocation of small amino acid or amino …