Immunomodulatory effect of adipose-derived stem cells: the cutting edge of clinical application
Adipose-derived stem cells (ASCs) represent a promising tool for soft tissue engineering as
well as for clinical treatment of inflammatory and autoimmune pathologies. The well …
well as for clinical treatment of inflammatory and autoimmune pathologies. The well …
Genetic stability of mesenchymal stromal cells for regenerative medicine applications: a fundamental biosafety aspect
S Neri - International journal of molecular sciences, 2019 - mdpi.com
Mesenchymal stem/stromal cells (MSC) show widespread application for a variety of clinical
conditions; therefore, their use necessitates continuous monitoring of their safety. The risk …
conditions; therefore, their use necessitates continuous monitoring of their safety. The risk …
Mesenchymal stem cell-derived extracellular vesicles attenuate influenza virus-induced acute lung injury in a pig model
M Khatri, LA Richardson, T Meulia - Stem cell research & therapy, 2018 - Springer
Background Mesenchymal stem (stromal) cells (MSCs) mediate their immunoregulatory and
tissue repair functions by secreting paracrine factors, including extracellular vesicles (EVs) …
tissue repair functions by secreting paracrine factors, including extracellular vesicles (EVs) …
MSC-derived extracellular vesicles attenuate immune responses in two autoimmune murine models: type 1 diabetes and uveoretinitis
Accumulating evidence shows that extracellular vesicles (EVs) produced by mesenchymal
stem/stromal cells (MSCs) exert their therapeutic effects in several disease models. We …
stem/stromal cells (MSCs) exert their therapeutic effects in several disease models. We …
[HTML][HTML] In situ delivery of apoptotic bodies derived from mesenchymal stem cells via a hyaluronic acid hydrogel: a therapy for intrauterine adhesions
L Xin, C Wei, X Tong, Y Dai, D Huang, J Chen, L Ma… - Bioactive materials, 2022 - Elsevier
Stem cell-based and stem cell-derived exosome-based therapies have shown promising
potential for endometrial regeneration and the clinical treatment of intrauterine adhesions …
potential for endometrial regeneration and the clinical treatment of intrauterine adhesions …
Engineering stem cells to produce exosomes with enhanced bone regeneration effects: an alternative strategy for gene therapy
Background Exosomes derived from stem cells have been widely studied for promoting
regeneration and reconstruction of multiple tissues as “cell-free” therapies. However, the …
regeneration and reconstruction of multiple tissues as “cell-free” therapies. However, the …
Role of epithelial cells in the pathogenesis and treatment of inflammatory bowel disease
R Okamoto, M Watanabe - Journal of gastroenterology, 2016 - Springer
In the past decades, continuous effort has been paid to deeply understanding the
pathophysiology of inflammatory bowel diseases (IBD), such as ulcerative colitis or Crohn's …
pathophysiology of inflammatory bowel diseases (IBD), such as ulcerative colitis or Crohn's …
Immunomodulatory fibrous hyaluronic acid‐Fmoc‐diphenylalanine‐based hydrogel induces bone regeneration
M Halperin‐Sternfeld, A Pokhojaev… - Journal of Clinical …, 2023 - Wiley Online Library
Aim To investigate the potential of an ultrashort aromatic peptide hydrogelator integrated
with hyaluronic acid (HA) to serve as a scaffold for bone regeneration. Materials and …
with hyaluronic acid (HA) to serve as a scaffold for bone regeneration. Materials and …
Concise review: is cardiac cell therapy dead? Embarrassing trial outcomes and new directions for the future
Stem cell therapy is a promising strategy for tissue regeneration. The therapeutic benefits of
cell therapy are mediated by both direct and indirect mechanisms. However, the application …
cell therapy are mediated by both direct and indirect mechanisms. However, the application …
Injection‐free delivery of MSC‐derived extracellular vesicles for myocardial infarction therapeutics
As emerging therapeutic factors, extracellular vesicles (EVs) offer significant potential for
myocardial infarction (MI) treatment. Current delivery approaches for EVs involve either intra …
myocardial infarction (MI) treatment. Current delivery approaches for EVs involve either intra …