Sex and gender disparities in bladder cancer have long been a subject of interest to the
cancer research community, wherein men have a 4 times higher incidence rate than women …

Simple Summary Bladder cancer is a heterogeneous disease that is composed of epithelia
with varying transcriptional, mutational and lineage signatures. The epithelia of bladder …

PURPOSE Homologous recombination repair gene mutations (HRRm) are common in
urothelial carcinoma (UC), rendering tumor cells sensitive to poly (ADP-ribose) polymerase …

Quiescent cancer cells (QCCs) reversibly reside in G 0 phase, thus allowing them to survive
chemotherapy and radiotherapy, which generally target proliferating cells. Surviving QCCs …

Proteomic analysis of urinary extracellular vesicles (EVs) is a powerful approach to discover
potential bladder cancer (BCa) biomarkers, however urine contains numerous EVs derived …

Simple Summary The Notch pathway is important in embryology and numerous tumor
diseases. However, its role in bladder cancer (BCa) has not been deeply investigated thus …

Simple Summary Urothelial cell carcinoma (UCC) is the ninth most common cancer
worldwide and in the US the fourth most common cancer, with~ 82,000 new cases (~ 62,000 …

Simple Summary Accurate, non-invasive methods that can diagnose bladder cancer (BC)
are needed to detect BC in its early stages and reduce the burden on patients with …

Background Men are three to four times more likely to be diagnosed with bladder cancer
(BCa) than women, who often have more aggressive tumors. Intravesical bacillus Calmette …

PURPOSE: To investigate the role of circulating rare cells (CRCs), including circulating
tumor cells (CTCs) and circulating endothelial cells (CECs), in aiding early intervention …