The role of B cells in atherosclerosis

AP Sage, D Tsiantoulas, CJ Binder… - Nature Reviews Cardiology, 2019 - nature.com
The cardiovascular system is subject to hyperlipidaemic, inflammatory, and pro-oxidant
stressors. Over time, these factors drive prevalent chronic diseases, of which atherosclerosis …

[HTML][HTML] Immunity, atherosclerosis and cardiovascular disease

J Frostegård - BMC medicine, 2013 - Springer
Atherosclerosis, the major cause of cardiovascular disease (CVD), is a chronic inflammatory
condition with immune competent cells in lesions producing mainly pro-inflammatory …

The immune system in atherosclerosis

GK Hansson, A Hermansson - Nature immunology, 2011 - nature.com
Cardiovascular disease, a leading cause of mortality worldwide, is caused mainly by
atherosclerosis, a chronic inflammatory disease of blood vessels. Lesions of atherosclerosis …

Infections, atherosclerosis, and coronary heart disease

NVK Pothineni, S Subramany, K Kuriakose… - European heart …, 2017 - academic.oup.com
Atherosclerosis is a chronic inflammatory disease. Pathophysiological similarities between
chronic infections and atherosclerosis triggered interest in a clinical association between …

Molecular biology of atherosclerosis

PN Hopkins - Physiological reviews, 2013 - journals.physiology.org
At least 468 individual genes have been manipulated by molecular methods to study their
effects on the initiation, promotion, and progression of atherosclerosis. Most clinicians and …

Adaptive response of T and B cells in atherosclerosis

DFJ Ketelhuth, GK Hansson - Circulation research, 2016 - Am Heart Assoc
Atherosclerosis is a chronic inflammatory disease that is initiated by the retention and
accumulation of cholesterol-containing lipoproteins, particularly low-density lipoprotein, in …

Oxidation-specific epitopes are danger-associated molecular patterns recognized by pattern recognition receptors of innate immunity

YI Miller, SH Choi, P Wiesner, L Fang… - Circulation …, 2011 - Am Heart Assoc
Oxidation reactions are vital parts of metabolism and signal transduction. However, they also
produce reactive oxygen species, which damage lipids, proteins and DNA, generating …

Systemic lupus erythematosus and cardiovascular disease

J Frostegård - Journal of Internal Medicine, 2023 - Wiley Online Library
The prognosis in systemic lupus erythematosus (SLE) has improved due to better treatment
and care, but cardiovascular disease (CVD) still remains an important clinical problem, since …

Generation and biological activities of oxidized phospholipids

VN Bochkov, OV Oskolkova, KG Birukov… - Antioxidants & redox …, 2010 - liebertpub.com
Glycerophospholipids represent a common class of lipids critically important for integrity of
cellular membranes. Oxidation of esterified unsaturated fatty acids dramatically changes …

Humoral immunity in atherosclerosis and myocardial infarction: from B cells to antibodies

F Porsch, Z Mallat, CJ Binder - Cardiovascular research, 2021 - academic.oup.com
Immune mechanisms are critically involved in the pathogenesis of atherosclerosis and its
clinical manifestations. Associations of specific antibody levels and defined B-cell subsets …