Genomic investigations of evolutionary dynamics and epistasis in microbial evolution experiments

ER Jerison, MM Desai - Current opinion in genetics & development, 2015 - Elsevier
Microbial evolution experiments enable us to watch adaptation in real time, and to quantify
the repeatability and predictability of evolution by comparing identical replicate populations …

Acinetobacter baylyi ADP1—naturally competent for synthetic biology

S Santala, V Santala - Essays in Biochemistry, 2021 - portlandpress.com
Acinetobacter baylyi ADP1 is a non-pathogenic soil bacterium known for its metabolic
diversity and high natural transformation and recombination efficiency. For these features, A …

Gene amplification, laboratory evolution, and biosensor screening reveal MucK as a terephthalic acid transporter in Acinetobacter baylyi ADP1

I Pardo, RK Jha, RE Bermel, F Bratti, M Gaddis… - Metabolic …, 2020 - Elsevier
Microbial terephthalic acid (TPA) catabolic pathways are conserved among the few bacteria
known to turnover this xenobiotic aromatic compound. However, to date there are few …

Insertion sequence-caused large-scale rearrangements in the genome of Escherichia coli

H Lee, TG Doak, E Popodi, PL Foster… - Nucleic acids …, 2016 - academic.oup.com
A majority of large-scale bacterial genome rearrangements involve mobile genetic elements
such as insertion sequence (IS) elements. Here we report novel insertions and excisions of …

The Genetic Analysis of an Acinetobacter johnsonii Clinical Strain Evidenced the Presence of Horizontal Genetic Transfer

S Montaña, STJ Schramm, GM Traglia, K Chiem… - PLoS …, 2016 - journals.plos.org
Acinetobacter johnsonii rarely causes human infections. While most A. johnsonii isolates are
susceptible to virtually all antibiotics, strains harboring a variety of β-lactamases have …

Horizontal Gene Transfer, Fitness Costs and Mobility Shape the Spread of Antibiotic Resistance Genes into Experimental Populations of Acinetobacter Baylyi

AL Sezmis, LC Woods, AY Peleg… - Molecular Biology and …, 2023 - academic.oup.com
Horizontal gene transfer (HGT) is important for microbial evolution, but how evolutionary
forces shape the frequencies of horizontally transferred genetic variants in the absence of …

Reduced social function in experimentally evolved Dictyostelium discoideum implies selection for social conflict in nature

TJ Larsen, I Jahan, DA Brock… - … of the Royal …, 2023 - royalsocietypublishing.org
Many microbes interact with one another, but the difficulty of directly observing these
interactions in nature makes interpreting their adaptive value complicated. The social …

Reduced mutation rate and increased transformability of transposon-free Acinetobacter baylyi ADP1-ISx

GA Suárez, BA Renda, A Dasgupta… - Applied and …, 2017 - Am Soc Microbiol
The genomes of most bacteria contain mobile DNA elements that can contribute to
undesirable genetic instability in engineered cells. In particular, transposable insertion …

Synthetic genome defenses against selfish DNA elements stabilize engineered bacteria against evolutionary failure

P Geng, SP Leonard, DM Mishler… - ACS Synthetic …, 2019 - ACS Publications
Mobile genetic elements drive evolution by disrupting genes and rearranging genomes.
Eukaryotes have evolved epigenetic mechanisms, including DNA methylation and RNA …

[HTML][HTML] Genomic mapping of ST85 blaNDM-1 and blaOXA-94 producing Acinetobacter baumannii isolates from Syrian Civil War Victims

T Salloum, E Tannous, S Alousi, H Arabaghian… - International Journal of …, 2018 - Elsevier
Objectives The rapid emergence of carbapenem-resistant Acinetobacter baumannii is a
global health concern. A comparative genomic analysis was performed on two ST85 A …