Structural plasticity of the hippocampus in response to estrogens in female rodents

PAS Sheppard, E Choleris, LAM Galea - Molecular brain, 2019 - Springer
It is well established that estrogens affect neuroplasticity in a number of brain regions. In
particular, estrogens modulate and mediate spine and synapse formation as well as …

New perspectives on sex differences in learning and memory

AW Fleischer, KM Frick - Trends in Endocrinology & Metabolism, 2023 - cell.com
Females have historically been disregarded in memory research, including the thousands of
studies examining roles for the hippocampus, medial prefrontal cortex, and amygdala in …

Intermittent fasting enhances long-term memory consolidation, adult hippocampal neurogenesis, and expression of longevity gene Klotho

GP Dias, T Murphy, D Stangl, S Ahmet, B Morisse… - Molecular …, 2021 - nature.com
Daily calorie restriction (CR) and intermittent fasting (IF) enhance longevity and cognition but
the effects and mechanisms that differentiate these two paradigms are unknown. We …

[HTML][HTML] Sex differences in the blood–brain barrier: implications for mental health

L Dion-Albert, LB Binder, B Daigle, A Hong-Minh… - Frontiers in …, 2022 - Elsevier
Prevalence of mental disorders, including major depressive disorder (MDD), bipolar
disorder (BD) and schizophrenia (SZ) are increasing at alarming rates in our societies …

The effect of high fat, high sugar, and combined high fat-high sugar diets on spatial learning and memory in rodents: A meta-analysis

KN Abbott, CK Arnott, RF Westbrook… - … & Biobehavioral Reviews, 2019 - Elsevier
Evidence from human and animal studies suggests that high-energy diets impair cognitive
function. However, the conditions for such impairments are unclear as studies have differed …

Sex differences in the development of the rodent corticolimbic system

H Premachandran, M Zhao… - Frontiers in …, 2020 - frontiersin.org
In recent years, a growing body of research has shown sex differences in the prevalence
and symptomatology of psychopathologies, such as depression, anxiety, and fear-related …

[HTML][HTML] Adult neurogenesis, human after all (again): Classic, optimized, and future approaches

PJ Lucassen, CP Fitzsimons, E Salta… - Behavioural brain …, 2020 - Elsevier
In this perspective article, we reflect on the recent debate about the existence of human
neurogenesis and discuss direct, and also indirect, support for the ongoing formation, and …

Sex differences in spatial learning and memory and hippocampal long-term potentiation at perforant pathway-dentate gyrus (PP-DG) synapses in Wistar rats

S Safari, N Ahmadi, R Mohammadkhani… - Behavioral and Brain …, 2021 - Springer
Background Recent studies show that gender may have a significant impact on brain
functions. However, the reports of sex effects on spatial ability and synaptic plasticity in …

The neurobiological basis of sex differences in learned fear and its inhibition

HLL Day, CW Stevenson - European Journal of Neuroscience, 2020 - Wiley Online Library
Learning that certain cues or environments predict threat enhances survival by promoting
appropriate fear and the resulting defensive responses. Adapting to changing stimulus …

Single housing‐induced effects on cognitive impairment and depression‐like behavior in male and female mice involve neuroplasticity‐related signaling

N Liu, Y Wang, AY An, C Banker… - European Journal of …, 2020 - Wiley Online Library
Single‐housed stress elicits a range of social isolation‐related behavioral and
neurobiological abnormalities. To investigate single housing‐induced behavioral changes …