Enhancing the therapeutic efficacy of nanoparticles for cancer treatment using versatile targeted strategies
Poor targeting of therapeutics leading to severe adverse effects on normal tissues is
considered one of the obstacles in cancer therapy. To help overcome this, nanoscale drug …
considered one of the obstacles in cancer therapy. To help overcome this, nanoscale drug …
The current state and future directions of RNAi-based therapeutics
The RNA interference (RNAi) pathway regulates mRNA stability and translation in nearly all
human cells. Small double-stranded RNA molecules can efficiently trigger RNAi silencing of …
human cells. Small double-stranded RNA molecules can efficiently trigger RNAi silencing of …
Recent advances in active targeting of nanomaterials for anticancer drug delivery
One of the challenges in cancer chemotherapy is the low target to non-target ratio of
therapeutic agents which incur severe adverse effect on the healthy tissues. In this regard …
therapeutic agents which incur severe adverse effect on the healthy tissues. In this regard …
Chitosan-based nanomaterials for drug delivery
This review discusses different forms of nanomaterials generated from chitosan and its
derivatives for controlled drug delivery. Nanomaterials are drug carriers with multiple …
derivatives for controlled drug delivery. Nanomaterials are drug carriers with multiple …
[HTML][HTML] Carrier-free nanodrugs with efficient drug delivery and release for cancer therapy: from intrinsic physicochemical properties to external modification
The considerable development of carrier-free nanodrugs has been achieved due to their
high drug-loading capability, simple preparation method, and offering “all-in-one” functional …
high drug-loading capability, simple preparation method, and offering “all-in-one” functional …
Advanced engineered nanoparticulate platforms to address key biological barriers for delivering chemotherapeutic agents to target sites
The widespread development of nanocarriers to deliver chemotherapeutics to specific tumor
sites has been motivated by the lack of selective targeting during chemotherapy inducing …
sites has been motivated by the lack of selective targeting during chemotherapy inducing …
RGD engineered dendrimer nanotherapeutic as an emerging targeted approach in cancer therapy
A Sheikh, S Md, P Kesharwani - Journal of Controlled Release, 2021 - Elsevier
A bird's eye view is now demanded in the area of cancer research to suppress the suffering
of cancer patient and mediate the lack of treatment related to chemotherapy. Chemotherapy …
of cancer patient and mediate the lack of treatment related to chemotherapy. Chemotherapy …
Functionalized chitosan for cancer nano drug delivery
Chitosan is a biotechnological derivative of chitin receiving a widespread pharmaceutical
and biomedical applications. It can be used to encapsulate and deliver cancer therapeutics …
and biomedical applications. It can be used to encapsulate and deliver cancer therapeutics …
Mitochondrial dysfunction and oxidative stress in Alzheimer's disease, and Parkinson's disease, Huntington's disease and amyotrophic lateral sclerosis-an updated …
T Alqahtani, SL Deore, AA Kide, BA Shende, R Sharma… - Mitochondrion, 2023 - Elsevier
Misfolded proteins in the central nervous system can induce oxidative damage, which can
contribute to neurodegenerative diseases in the mitochondria. Neurodegenerative patients …
contribute to neurodegenerative diseases in the mitochondria. Neurodegenerative patients …
Exosome-based drug delivery systems and their therapeutic applications
In the past few decades, scientists have actively worked on developing effective drug
delivery systems (DDSs) as means to control life-threatening diseases and challenging …
delivery systems (DDSs) as means to control life-threatening diseases and challenging …