Extracellular matrices (ECM s) are highly specialized and dynamic three‐dimensional (3D)
scaffolds into which cells reside in tissues. ECM is composed of a variety of fibrillar …

The efficient healing of skin wounds is crucial for securing the vital barrier function of the
skin, but pathological wound healing and scar formation are major medical problems …

The endogenous electric field (EF) generated by transepithelial potential difference plays a
decisive role in wound reepithelialization. For patients with large or chronic wounds …

Background Hypertrophic scar (HS) is a fibro-proliferative disorder of dermis after burn or
trauma and usually leads to esthetic disfiguration and functionary impairment for patients …

Excessive extracellular matrix deposition drives fibroblasts into a state of high mechanical
stress, exacerbating pathological fibrosis and hypertrophic scar formation, leading to tissue …

Excessive scar formation has adverse physiological and psychological effects on patients;
therefore, a therapeutic strategy for rapid wound healing and reduced scar formation is …

Objectives Skin serves as the major interface between the external environment and body
which is liable to many kinds of injuries. Mesenchymal stem cell (MSC) therapy has been …

Tissue fibrosis is the deposition of excessive extracellular matrix and can occur as part of the
body's natural wound healing process upon injury, or as a consequence of diseases such as …

Abstract In-situ three-dimensional (3D) bioprinting has been emerging as a promising
technology designed to rapidly seal cutaneous defects according to their contour …

Injuries to our skin trigger a cascade of spatially-and temporally-synchronized healing
processes. During such endogenous wound repair, the role of fibroblasts is multifaceted …