Epigenetic regulation in metabolic diseases: mechanisms and advances in clinical study

YL Wu, ZJ Lin, CC Li, X Lin, SK Shan, B Guo… - … and Targeted Therapy, 2023 - nature.com
Epigenetics regulates gene expression and has been confirmed to play a critical role in a
variety of metabolic diseases, such as diabetes, obesity, non-alcoholic fatty liver disease …

Role of diet in hyperuricemia and gout

A Danve, ST Sehra, T Neogi - Best practice & research Clinical …, 2021 - Elsevier
Background Gout is the most common form of inflammatory arthritis, affecting 41 million
adults worldwide. The global burden of gout has been increasing over the last three …

[HTML][HTML] Therapeutic effect of berberine on metabolic diseases: Both pharmacological data and clinical evidence

X Xu, H Yi, J Wu, T Kuang, J Zhang, Q Li, H Du… - Biomedicine & …, 2021 - Elsevier
The increased incidence of metabolic diseases (eg, diabetes and obesity) has seriously
affected human health and life safety worldwide. It is of great significance to find effective …

Efficacy and Safety of Curcumin and Curcuma longa Extract in the Treatment of Arthritis: A Systematic Review and Meta-Analysis of Randomized Controlled Trial

L Zeng, T Yang, K Yang, G Yu, J Li, W Xiang… - Frontiers in …, 2022 - frontiersin.org
Background Modern pharmacological research found that the chemical components of
Curcuma longa L. are mainly curcumin and turmeric volatile oil. Several recent randomized …

[HTML][HTML] A review on benefits of quercetin in hyperuricemia and gouty arthritis

T Nutmakul - Saudi Pharmaceutical Journal, 2022 - Elsevier
Hyperuricemia becomes a public health problem worldwide. It is not only a major risk factor
for gout but also associated with the development of life-threatening diseases such as …

Gouty arthropathy: review of clinical manifestations and treatment, with emphasis on imaging

JS Weaver, ER Vina, PL Munk, AS Klauser… - Journal of Clinical …, 2021 - mdpi.com
Gout, a crystalline arthropathy caused by the deposition of monosodium urate crystals in the
articular and periarticular soft tissues, is a frequent cause of painful arthropathy. Imaging has …

Exploration, sequence optimization and mechanism analysis of novel xanthine oxidase inhibitory peptide from Ostrea rivularis Gould

Q Zhao, X Jiang, Z Mao, J Zhang, J Sun, X Mao - Food Chemistry, 2023 - Elsevier
Xanthine oxidase (XO) inhibitory peptides are secure and efficient functional food
ingredients for treating or alleviating hyperuricemia (HUA). In this study, ultrafiltration and …

Safety and efficacy of probiotic supplementation in 8 types of inflammatory arthritis: A systematic review and meta-analysis of 34 randomized controlled trials

L Zeng, Y Deng, Q He, K Yang, J Li, W Xiang… - Frontiers in …, 2022 - frontiersin.org
Objective To evaluate Safety and efficacy of probiotic supplementation in inflammatory
arthritis. Methods The literature on the treatment of inflammatory arthritis with probiotics has …

A review on gout: Looking back and looking ahead

H Tao, Y Mo, W Liu, H Wang - International Immunopharmacology, 2023 - Elsevier
Gout is a metabolic disease caused by the deposition of monosodium urate (MSU) crystals
inside joints, which leads to inflammation and tissue damage. Increased concentration of …

Causal relationship between gut microbiota and gout: a two-sample Mendelian randomization study

M Wang, J Fan, Z Huang, D Zhou, X Wang - Nutrients, 2023 - mdpi.com
Gout is a form of prevalent and painful inflammatory arthritis characterized by elevated
serum urate (SUA) levels. The gut microbiota (GM) is believed to influence the development …