[HTML][HTML] Staphylococcus aureus host interactions and adaptation

BP Howden, SG Giulieri, T Wong Fok Lung… - Nature Reviews …, 2023 - nature.com
Invasive Staphylococcus aureus infections are common, causing high mortality,
compounded by the propensity of the bacterium to develop drug resistance. S. aureus is an …

Microbiota and maintenance of skin barrier function

TA Harris-Tryon, EA Grice - Science, 2022 - science.org
Human skin forms a protective barrier against the external environment and is our first line of
defense against toxic, solar, and pathogenic insults. Our skin also defines our outward …

[HTML][HTML] Atopic dermatitis: an expanding therapeutic pipeline for a complex disease

T Bieber - Nature reviews Drug discovery, 2022 - nature.com
Atopic dermatitis (AD) is a common chronic inflammatory skin disease with a complex
pathophysiology that underlies a wide spectrum of clinical phenotypes. AD remains …

Staphylococcus epidermidis and its dual lifestyle in skin health and infection

MM Severn, AR Horswill - Nature Reviews Microbiology, 2023 - nature.com
The coagulase-negative bacterium Staphylococcus epidermidis is a member of the human
skin microbiota. S. epidermidis is not merely a passive resident on skin but actively primes …

The microbiome-shaping roles of bacteriocins

S Heilbronner, B Krismer, H Brötz-Oesterhelt… - Nature Reviews …, 2021 - nature.com
The microbiomes on human body surfaces affect health in multiple ways. They include not
only commensal or mutualistic bacteria but also potentially pathogenic bacteria, which can …

Disease modification in inflammatory skin disorders: opportunities and challenges

T Bieber - Nature Reviews Drug Discovery, 2023 - nature.com
Progress in understanding of the mechanisms underlying chronic inflammatory skin
disorders, such as atopic dermatitis and psoriasis vulgaris, has led to new treatment options …

Skin microbiome of atopic dermatitis

LF Koh, RY Ong, JE Common - Allergology International, 2022 - jstage.jst.go.jp
abstract The skin microbiome is a key component of pathogenesis in atopic dermatitis (AD).
The skin of AD patients is characterized by microbial dysbiosis, with a reduction of microbial …

[HTML][HTML] The human skin microbiome in selected cutaneous diseases

S Carmona-Cruz, L Orozco-Covarrubias… - Frontiers in cellular …, 2022 - frontiersin.org
The human skin harbors a wide variety of microbes that, together with their genetic
information and host interactions, form the human skin microbiome. The role of the human …

Novel insights into atopic dermatitis

CF Schuler IV, AC Billi, E Maverakis, LC Tsoi… - Journal of Allergy and …, 2023 - Elsevier
Recent research into the pathophysiology and treatment of atopic dermatitis (AD) has shown
notable progress. An increasing number of aspects of the immune system are being …

Systematic mining of the human microbiome identifies antimicrobial peptides with diverse activity spectra

AM King, Z Zhang, E Glassey, P Siuti, J Clardy… - Nature …, 2023 - nature.com
Human-associated bacteria secrete modified peptides to control host physiology and
remodel the microbiota species composition. Here we scanned 2,229 Human Microbiome …