Immune responses to human fungal pathogens and therapeutic prospects

MS Lionakis, RA Drummond, TM Hohl - Nature Reviews Immunology, 2023 - nature.com
Pathogenic fungi have emerged as significant causes of infectious morbidity and death in
patients with acquired immunodeficiency conditions such as HIV/AIDS and following receipt …

Pathogenesis and virulence of Candida albicans

JP Lopes, MS Lionakis - Virulence, 2022 - Taylor & Francis
Candida albicans is a commensal yeast fungus of the human oral, gastrointestinal, and
genital mucosal surfaces, and skin. Antibiotic-induced dysbiosis, iatrogenic …

[HTML][HTML] Invasive candidiasis

PG Pappas, MS Lionakis, MC Arendrup… - Nature Reviews …, 2018 - nature.com
Invasive candidiasis is an important health-care-associated fungal infection that can be
caused by several Candida spp.; the most common species is Candida albicans, but the …

[HTML][HTML] Immune defence to invasive fungal infections: A comprehensive review

B Pathakumari, G Liang, W Liu - Biomedicine & Pharmacotherapy, 2020 - Elsevier
The fungal infections are relatively common in humans that can range from common, mild
superficial infections to life-threatening invasive infections. Most of the pathogenic fungi are …

Staphylococcus aureus Vaccine Research and Development: The Past, Present and Future, Including Novel Therapeutic Strategies

J Clegg, E Soldaini, RM McLoughlin… - Frontiers in …, 2021 - frontiersin.org
Staphylococcus aureus is one of the most important human pathogens worldwide. Its high
antibiotic resistance profile reinforces the need for new interventions like vaccines in …

Development of a vaccine against Staphylococcus aureus invasive infections: Evidence based on human immunity, genetics and bacterial evasion mechanisms

LS Miller, VG Fowler Jr, SK Shukla… - FEMS microbiology …, 2020 - academic.oup.com
Invasive Staphylococcus aureus infections are a leading cause of morbidity and mortality in
both hospital and community settings, especially with the widespread emergence of virulent …

Candida albicans and Staphylococcus Species: A Threatening Twosome

H Carolus, K Van Dyck, P Van Dijck - Frontiers in microbiology, 2019 - frontiersin.org
Candida albicans and Staphylococcus species are, respectively, the most common fungal
and bacterial agents isolated from bloodstream infections, worldwide. Moreover, it has been …

IL-17–Mediated immunity to the opportunistic fungal pathogen Candida albicans

HR Conti, SL Gaffen - The Journal of Immunology, 2015 - journals.aai.org
Abstract IL-17 (IL-17A) has emerged as a key mediator of protection against extracellular
microbes, but this cytokine also drives pathology in various autoimmune diseases …

Immunity to fungal infections

L Romani - Nature Reviews Immunology, 2011 - nature.com
Fungal diseases represent an important paradigm in immunology, as they can result from
either a lack of recognition by the immune system or overactivation of the inflammatory …

Vulvovaginal Candida albicans infections: pathogenesis, immunity and vaccine prospects

A Cassone - BJOG: An International Journal of Obstetrics & …, 2015 - Wiley Online Library
Although a number of fungal species belonging to the genus C andida can cause acute
vulvovaginal infection (VVC), C andida albicans is by far the most prevalent etiological …