Emerging roles of long non‐coding RNA in cancer
A Sanchez Calle, Y Kawamura, Y Yamamoto… - Cancer …, 2018 - Wiley Online Library
Since comprehensive analysis of the mammalian genome revealed that the majority of
genomic products are transcribed in long non‐coding RNA (lnc RNA), increasing attention …
genomic products are transcribed in long non‐coding RNA (lnc RNA), increasing attention …
Nuclear long noncoding RNAs: key regulators of gene expression
A significant portion of the human genome encodes genes that transcribe long nonprotein-
coding RNAs (lncRNAs). A large number of lncRNAs localize in the nucleus, either enriched …
coding RNAs (lncRNAs). A large number of lncRNAs localize in the nucleus, either enriched …
MALAT1: a druggable long non-coding RNA for targeted anti-cancer approaches
The deeper understanding of non-coding RNAs has recently changed the dogma of
molecular biology assuming protein-coding genes as unique functional biological effectors …
molecular biology assuming protein-coding genes as unique functional biological effectors …
Long noncoding RNA MALAT1 in exosomes drives regenerative function and modulates inflammation-linked networks following traumatic brain injury
Background Neuroinflammation is a common therapeutic target for traumatic brain injury
(TBI) due to its contribution to delayed secondary cell death and has the potential to occur …
(TBI) due to its contribution to delayed secondary cell death and has the potential to occur …
Regulation of pleiotropic physiological roles of nitric oxide signaling
L Soundararajan, A Dharmarajan, P Samji - Cellular signalling, 2023 - Elsevier
Nitric Oxide (NO) is a highly diffusible, ubiquitous signaling molecule and a free radical that
is naturally synthesized by our body. The pleiotropic effects of NO in biological systems are …
is naturally synthesized by our body. The pleiotropic effects of NO in biological systems are …
Phase separation drives X-chromosome inactivation: a hypothesis
The long non-coding RNA Xist induces heterochromatinization of the X chromosome by
recruiting repressive protein complexes to chromatin. Here we gather evidence, from the …
recruiting repressive protein complexes to chromatin. Here we gather evidence, from the …
[HTML][HTML] The evolution of long noncoding RNA acceptance in prostate cancer initiation, progression, and its clinical utility in disease management
VR Ramnarine, M Kobelev, EA Gibb, M Nouri, D Lin… - European urology, 2019 - Elsevier
Context It is increasingly evident that non–protein-coding regions of the genome can give
rise to transcripts that form functional layers of the cancer genome. One of most abundant …
rise to transcripts that form functional layers of the cancer genome. One of most abundant …
Estrogen receptor β promotes the vasculogenic mimicry (VM) and cell invasion via altering the lncRNA-MALAT1/miR-145-5p/NEDD9 signals in lung cancer
W Yu, J Ding, M He, Y Chen, R Wang, Z Han, EZ Xing… - Oncogene, 2019 - nature.com
While estrogen receptor β (ERβ) may impact the progression of non-small cell lung cancer
(NSCLC), its linkage to alteration of the vasculogenic mimicry (VM) formation to influence the …
(NSCLC), its linkage to alteration of the vasculogenic mimicry (VM) formation to influence the …
The role and mechanism of epithelial-to-mesenchymal transition in prostate cancer progression
In prostate cancer (PCa), similar to many other cancers, distant organ metastasis symbolizes
the beginning of the end disease, which eventually leads to cancer death. Many …
the beginning of the end disease, which eventually leads to cancer death. Many …
Non-coding RNAs: long non-coding RNAs and microRNAs in endocrine-related cancers
CM Klinge - Endocrine-related cancer, 2018 - erc.bioscientifica.com
The human genome is 'pervasively transcribed'leading to a complex array of non-coding
RNAs (ncRNAs) that far outnumber coding mRNAs. ncRNAs have regulatory roles in …
RNAs (ncRNAs) that far outnumber coding mRNAs. ncRNAs have regulatory roles in …