Since HIV was identified as the etiological agent of AIDS, there have been significant
advances in antiretroviral therapy (ART) that has reduced morbidity/mortality. Still, the viral …

Background Simplified antiretroviral therapy (ART) regimens are desirable for people with
HIV. We investigated the efficacy and safety of switching from triple ART to dual dolutegravir …

Background: Antiretroviral therapy has increasingly improved management of HIV infection,
ensuring long-term efficacy and tolerability. Each class of antiretrovirals has, however …

HIV is a global deliberating infectious disease. Of note, more than 36 million people living
with HIV (PLHIV) with approximately newly diagnosed 1.5 million cases annually. M184V is …

Background: The introduction of tenofovir alafenamide (TAF) in antiretroviral therapy has
deeply modified the choice of the backbone for different treatment regimens, allowing the …

Background: Physical activity could increase the production of oxidative stress biomarkers,
affecting the metabolism and excretion of antiretroviral drugs and, consequently, the clinical …

Background Integrase strand transferase inhibitors (INSTI), including raltegravir (RAL),
elvitegravir (ELV), and dolutegravir (DTG), have demonstrated better efficacy and tolerability …

Emerging viruses are a public health threat best managed with broad spectrum antivirals.
Common viral structures, like capsids or virion envelopes, have been proposed as targets …

Introduction Second-generation integrase strand transfer inhibitors (INSTIs) are preferred
treatment options worldwide, and dolutegravir (DTG) is the treatment of choice in resource …

Background: Dual anti-retroviral therapy is the main proven valuable intervention type for
treating naïve HIV/AIDS. Currently, no high-quality evidence is available regarding the best …