The contribution of periaqueductal gray in the regulation of physiological and pathological behaviors

H Zhang, Z Zhu, WX Ma, LX Kong, PC Yuan… - Frontiers in …, 2024 - frontiersin.org
Periaqueductal gray (PAG), an integration center for neuronal signals, is located in the
midbrain and regulates multiple physiological and pathological behaviors, including pain …

Dissecting neural circuits from rostral ventromedial medulla to spinal trigeminal nucleus bidirectionally modulating craniofacial mechanical sensitivity

Y Xue, S Mo, Y Li, Y Cao, X Xu, Q Xie - Progress in Neurobiology, 2024 - Elsevier
Chronic craniofacial pain is intractable and its mechanisms remain unclarified. The rostral
ventromedial medulla (RVM) plays a crucial role in descending pain facilitation and …

Understanding of Spinal Wide Dynamic Range Neurons and Their Modulation on Pathological Pain

Z Zhang, H Zheng, Q Yu, X Jing - Journal of Pain Research, 2024 - Taylor & Francis
The spinal dorsal horn (SDH) transmits sensory information from the periphery to the brain.
Wide dynamic range (WDR) neurons within this relay site play a critical role in modulating …

Alamandine injection in the periaqueductal gray and rostral ventromedial medulla attenuates allodynia induced by sciatic nerve ligation in rats

Z Gholami, AS Hekmat, A Abbasi, K Javanmardi - Neuroscience Letters, 2024 - Elsevier
Alamandine, a peptide known to interact with Mas-related G protein-coupled receptor
subtype D (MrgD), has been implicated in moderating inflammatory signals. MrgD receptors …

Spontaneous oxycodone withdrawal disrupts sleep, circadian, and electrophysiological dynamics in rats

M Gulledge, WA Carlezon Jr, RK McHugh, M Prerau… - bioRxiv, 2024 - biorxiv.org
Opioid dependence is defined by an aversive withdrawal syndrome upon drug cessation
that can motivate continued drug-taking, development of opioid use disorder, and precipitate …